Actively Recruiting

All Genders
Healthy Volunteers
NCT06862843

Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.

Led by Meyer Children's Hospital IRCCS · Updated on 2025-03-06

90

Participants Needed

4

Research Sites

92 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The proposed study is part of a PNRR 2022 project (call "Non-Communicable Chronic Diseases (NCDs) with high impact on healthcare and social assistance systems," currently awaiting funding response) and represents the continuation of an observational clinical study named TRANSMIC, approved by the pediatric ethics committee of the Tuscany region. TRANSMIC was an integral part of a European research project within the joint programming initiative (JPI), under the HDHL-INTIMIC theme: "A Healthy Diet for a Healthy Life," aimed at understanding the cause-effect relationships between diet, gut microbiome, and human health. Understanding the role of diet in inflammatory bowel diseases (IBD) and exploring its role in autoimmune inflammatory conditions with joint manifestations, such as JIA, provides additional insights into the development, progression, and management of these conditions, opening new horizons for the use of dietary treatments in preventing these inflammatory conditions.

CONDITIONS

Official Title

Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Families with at least one child or adult affected by inflammatory bowel disease (IBD) or juvenile idiopathic arthritis (JIA)
  • Father and mother with children aged between 0 and 18 years, in good health
  • At least one adult or child affected by IBD, or a child affected by JIA, regardless of therapy or disease severity
  • Healthy families with father and mother and children aged 0 to 18 years, in good health and without chronic inflammatory or autoimmune diseases
Not Eligible

You will not qualify if you...

  • For subjects with IBD: monogenic disease
  • For subjects with IBD: children with an ileostomy or who have undergone colectomy
  • For healthy subjects: any chronic inflammatory bowel disease, autoimmune disease, or ongoing infectious disease
  • No exclusion criteria for subjects with JIA

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

AOU Meyer IRCCS

Florence, Italy, Italy

Actively Recruiting

2

Università La Sapienza di Roma

Roma, Roma, Italy, 00185

Actively Recruiting

3

Università di Foggia

Foggia, Italy

Actively Recruiting

4

Ospedale Villa Sofia Cervello, Università di Palermo

Palermo, Italy

Actively Recruiting

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Research Team

P

Paolo Lionetti, MD, PhD, Ordinary Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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