Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID06154356

Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Parkinson's Disease, Randomized Controlled Trial

Led by Karamanoğlu Mehmetbey University · Updated on 2025-12-11

54

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

K

Karamanoğlu Mehmetbey University

Lead Sponsor

K

Karaman Training and Research Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Parkinson's disease (PD) is a progressive neurological condition that often leads to gait and balance problems, increasing the risk of falls and reducing independence and quality of life. Researchers are evaluating whether adding action observation (AO) and motor imagery (MI) therapies to standard rehabilitation can improve balance, functional status, and quality of life in people with PD. These therapies use the brain's mirror neuron system to help relearn motor skills by watching and imagining movements. Participants will receive either AO and MI therapy alongside conventional rehabilitation or a sham version of these therapies with conventional rehabilitation. The AO therapy involves watching videos of specific exercises with music, followed by imagining and then performing these movements. The sham therapy involves watching static nature photographs with music and imagining those images before doing limited repetitions of the exercises. Both therapies focus on upper and lower extremity movements and are designed to be comparable except for the active treatment. During the six-week study, participants will be evaluated before and after rehabilitation on balance and functional tests such as the Berg Balance Scale, Unified Parkinson's Disease Rating Scale, Timed Up and Go Test, and Five Times Sit to Stand Test. Quality of life and freezing of gait will also be assessed through questionnaires. The study will monitor changes in these measures to understand the impact of AO and MI therapy in PD rehabilitation programs.

CONDITIONS

Brief Title

Action Observation and Motor Imagery Therapy in Parkinson's Disease

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a diagnosis of Parkinson's Disease
  • Hoehn and Yahr Stage 1-3
  • Aged between 18 and 65 years
  • Able to follow simple verbal instructions
Not Eligible

You will not qualify if you...

  • Cognitive dysfunction preventing following simple verbal instructions
  • Severe hearing problems
  • Severe vision problems
  • Musculoskeletal conditions affecting physical performance, such as amputation, severe joint mobility limitation, or peripheral nerve damage
  • Uncontrolled hypertension or diabetes mellitus
  • History of symptomatic lung disease such as asthma, chronic obstructive pulmonary disease, or emphysema
  • History of symptomatic cardiac disease such as coronary artery disease, arrhythmia, or heart failure

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 weeks

Participants receive action observation and motor imagery therapy or sham therapy in addition to conventional rehabilitation programs to improve balance, functional status, and quality of life.

Weekly visits for up to 6 weeks

Trial Site Locations

Total: 1 location

1

Karaman Training and Research Hospital

Karaman, Karaman, Turkey (Türkiye), 70200

Actively Recruiting

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Research Team

Y

Yurdagul Bahran Mustu, MD.

A

Aynur Basaran, MD, Prof.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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