Actively Recruiting

Age: 14Years +
All Genders
ID06120907

Swiss Itch Registry (SWITCHR) - A Prospective Registry to Collect Data of Patients With Chronic Pruritus

Led by University Hospital, Basel, Switzerland · Updated on 2024-12-13

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to create a national registry for patients with chronic pruritus (CP), which is a persistent itch lasting more than 6 weeks and linked to various skin and non-skin conditions. Chronic pruritus significantly affects quality of life and carries a high socio-economic burden. The registry will help improve medical care, enable standardized comparisons of different pruritic conditions nationally and internationally, and raise awareness among healthcare providers and authorities in Switzerland. Participants in this observational study will have various data collected at defined times, including patient-reported outcomes, physician assessments, blood tests, and 3D photodocumentation. Additional tests like skin biopsies, neurophysiological evaluations, and radiological imaging may be performed if needed. The study focuses on gathering clinical, biological, and image-based data to understand patient needs, disease mechanisms, treatment results, and safety aspects. During the study, participants will be monitored up to 60 months with assessments involving questionnaires measuring quality of life, itch severity, sleep disturbances, anxiety, and skin condition severity. Researchers will also use imaging and sensory testing to track changes over time. The long-term data will support retrospective analyses, with ongoing evaluation of treatment outcomes and patient health status throughout the study period.

CONDITIONS

Brief Title

Swiss Itch Registry

Who Can Participate

Age: 14Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age �3E�3D 14 years
  • Written informed consent of the patient
  • Diagnosis of chronic pruritus irrespective of the International Forum for the Study of Itch (IFSI) group and/or underlying cause
  • Itch intensity of at least 4 on a Numerical Rating Scale within the last 7 days
  • Sufficient language skills to provide informed consent
Not Eligible

You will not qualify if you...

  • Any medical or psychological condition that may prevent participation according to the treating physician
  • Lack of informed consent for registry participation
  • Refusal to complete Patient Reported Outcomes (PROs)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 60 months

Participants are observed over time with regular data collection including phenotypic data, treatments administered, response to treatment, three-dimensional total body images, biopsies, and blood plasma samples.

Periodic visits for data collection over up to 5 years

Trial Site Locations

Total: 1 location

1

Department of Dermatology, University Hospital Basel

Basel, Switzerland, 4055

Actively Recruiting

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Research Team

S

Simon Mueller, PD Dr. med.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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