Actively Recruiting

Age: 40Years - 70Years
All Genders
ID04912739

Targeted Health Dialogues in Primary Care: Lifestyle Screening and Molecular Profiling for a Healthier Life

Led by Region Skane · Updated on 2025-06-25

18000

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a prevention program called Targeted Health Dialogues aimed at improving cardiovascular health and reducing serious diseases, including cancer, in middle-aged adults living in Skåne, Sweden. This observational study integrates health dialogues, clinical and laboratory data collection, and detailed questionnaires about health behaviors, diet, and lifestyle. The study links individual data with national and regional health records, including hospital admissions, diagnoses, prescriptions, sociodemographic factors, and family relations, to better understand disease risk and intervention effects. The program includes health dialogues led by specially trained staff, where participants first complete questionnaires and undergo measurements like blood pressure, BMI, waist-to-hip ratio, and blood tests for glucose and cholesterol. A "health curve" summarizes these results and is discussed during the dialogue. A subgroup also provides blood samples for molecular biomarker analysis. The study is enrolling all 40-, 50-, 60-, and 70-year-old residents registered at healthcare centers in Skåne. Participants provide health information through questionnaires and physical assessments, while researchers collect and link extensive health and demographic data over time. The primary outcomes focus on the impact of the health dialogues on cardiovascular disease and cancer incidence by 2035. Secondary outcomes include associations between risk factors and diseases, biomarker identification, health behavior changes, and public health profiling. The study will monitor participants long-term to evaluate and refine personalized prevention approaches.

CONDITIONS

Brief Title

Targeted Health Dialogues in Primary Care

Who Can Participate

Age: 40Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 40-, 50-, 60-, and 70-year old men and women
  • Registered at a healthcare center in Skåne county
Not Eligible

You will not qualify if you...

  • Unable to understand written study information and give informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - Single session

Participants complete a detailed questionnaire and undergo measurements including blood glucose, cholesterol, BMI, waist-to-hip ratio, and blood pressure. They then discuss their health results with specially trained healthcare personnel in a targeted health dialogue. A sub-group provides additional blood samples for molecular analyses.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 10 years

Participants are observed over time through linkage of collected data with national and regional health records to evaluate health outcomes and the effects of targeted health dialogues.

No scheduled visits; data collected through health records

Trial Site Locations

Total: 1 location

1

Center for Primary Health Care Research, Lund University and Region Skåne

Malmö, Skåne County, Sweden, 20502

Actively Recruiting

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Research Team

K

Kristina Sundquist, PhD, MD

E

Emelie Stenman, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Exploring the link between self-rated poor oral health and cardiovascular risk: a cross-sectional study using SCORE2.

Peter Nymberg, Veronica Milos-Nymberg, Anton Grundberg...

https://pubmed.ncbi.nlm.nih.gov/39994610

Health determinants among participants in targeted health dialogues offered to all 40-year-old individuals in a metropolitan region of 1.4 million people.

Emelie Stenman, Beata Borgström Bolmsjö, Anton Grundberg...

https://pubmed.ncbi.nlm.nih.gov/39091122