Actively Recruiting
Project THRIVE: Testing an App-based Early Intervention to Reduce Alcohol Use and PTSD After Sexual Assault
Led by University of Washington · Updated on 2025-02-11
464
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
N
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating different versions of the THRIVE app, an app-based early intervention designed to reduce alcohol misuse and posttraumatic stress symptoms in people who have recently experienced sexual assault. This randomized study aims to find the most effective and efficient app version. The THRIVE app is currently only available to participants in this trial, which is sponsored by the University of Washington. Participants will be randomly assigned to use one of several versions of the THRIVE app for 21 days. Different groups receive various combinations of app modules, including Activities, Thoughts, Coaching calls, or non-core intervention components. Coaching calls last 10-20 minutes weekly and support app use and symptom monitoring. All participants complete daily brief surveys on PTSD symptoms and alcohol use during the app use period. During the study, participants will be monitored at baseline and at multiple time points up to one year. Researchers assess alcohol use patterns, posttraumatic stress symptom severity, and provisional PTSD diagnosis regularly. Secondary outcomes include drug and cannabis use, depression, and anxiety symptoms. Participants engage with the app daily and receive coaching support as assigned, with ongoing safety and referral resources provided throughout the trial.
CONDITIONS
Brief Title
Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be 18 years or older
- Be able to read and speak English fluently
- Own a smartphone that only you can access while the study app is installed or agree to reduce access risk
- Be an enrolled undergraduate or graduate student at a recruitment site during screening or plan to enroll in the upcoming fall term
- Reside in the same state as the recruitment site for most of the year
- Have experienced a sexual assault within the past 12 weeks
- Report at least one heavy drinking episode in the past month (5+ drinks/day or 15+/week for males; 4+/day or 8+/week for females or intersex at birth)
- Endorse elevated posttraumatic stress symptoms at screening above a pre-established cutoff
You will not qualify if you...
- Active psychosis
- Located outside of the US at the time of screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - 21 days
Participants use the THRIVE app for 21 days, engaging with various behavioral modules depending on their assigned group, including activity scheduling, cognitive restructuring, and weekly coaching calls. All participants complete brief daily self-report surveys on PTSD symptoms and alcohol use during this period.
Daily app interactions and weekly coaching calls (4 calls total including enrollment call)
Duration - Up to 1 year
Participants complete follow-up assessments of alcohol use, PTSD symptoms, and other related outcomes at multiple time points after the treatment period to monitor progress and impact over time.
Follow-up assessments at 1 month, 3 months, 6 months, 9 months, and 12 months
Trial Site Locations
Total: 1 location
1
University of Washington
Seattle, Washington, United States, 98195
Actively Recruiting
Research Team
E
Emily Dworkin, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
PREVENTION
Number of Arms
8
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