Effect of Adding Whole Body Vibration to Vitamin D and Colchicine Treatment in Adolescent Girls with Familial Mediterranean Fever

What this Trial Is About

Familial Mediterranean Fever FMF is a condition common in the Mediterranean region that affects adolescents, leading to reduced physical function, cardiorespiratory fitness, muscle strength, and bone mass. This research aims to explore whether adding whole body vibration therapy to the usual vitamin D and colchicine treatment can improve these health outcomes in adolescent girls with FMF. The study involves two groups of 20 adolescent girls with FMF each. Both groups will receive daily vitamin D supplements and their regular colchicine medication for six months. One group, called the vibration group, will also participate in three 20-minute sessions of whole body vibration each week during the same six-month period, while the control group will receive only the vitamin D and colchicine treatment. Participants will be monitored over six months, with assessments including bone mineral density, vitamin D levels, osteoprotegerin, quadriceps muscle strength, and physical performance tests like the standing long jump and sit-to-stand tests. These measurements will help researchers evaluate the impact of adding whole body vibration to standard care. The study includes randomized assignment to groups and single masking to maintain study integrity, with participation lasting six months from start to finish.

is There an Effect of Adding Body Vibration to Intake of Vitamin D on Some Outcomes of Familial Mediterranean Fever