An Overview of Heart Rate Variability Metrics and Norms.
Fred Shaffer, J P Ginsberg
https://pubmed.ncbi.nlm.nih.gov/29034226/Actively Recruiting
Led by University of California, Irvine · Updated on 2026-03-18
210
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to evaluate the impact of a community health worker-led coaching program called GRIT on preventing early regular use of alcohol and cannabis among adolescents aged 11 to 14 who have experienced significant adversity and do not regularly use these substances at the start. The study focuses on youth impacted by high exposure to adverse childhood experiences ACEs, which can lead to difficulties in managing emotions and behaviors, increasing the risk of early substance use and related health issues. Researchers will compare GRIT with an active control program focused on digital citizenship to assess effects on self-regulation and cardiometabolic risks. Participants will be randomly assigned to either the GRIT intervention or the Digital Citizenship Curriculum. The GRIT program involves six weekly 60-minute sessions delivered via Zoom by community health workers, teaching coping and self-regulation skills using heart rate variability biofeedback and promoting healthy habits. The Digital Citizenship Curriculum also consists of six weekly sessions focused on navigating digital life. Participants attend three in-person visits at the start, immediately after the intervention, and 12 months later, with an optional booster session six months post-intervention. Throughout the study, participants complete heart rate variability assessments, surveys, and online questionnaires at multiple time points including baseline, post-intervention, six months, and 12 months post-intervention. Researchers will measure substance use, emotional regulation, sleep quality, nutrition, physical activity, family functioning, psychological flexibility, and stress levels. The study includes ongoing monitoring of participant progress and effects over a full year after the intervention to understand its impact on preventing substance use and improving health.
CONDITIONS
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
D
Dawn T. Bounds, Ph.D.
J
Jenny Fotang
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University of California, Irvine
Lead Sponsor
University of California, Los Angeles
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | GRIT Intervention | Digital Citizenship Curriculum (DCC) |
|---|---|---|
| What it is | A 6-session, family-based psychoeducational program designed for youth with high-risk ACEs and their caregivers, focused on resilience promotion, health coaching, psychoeducation, and heart rate variability biofeedback, delivered by a community health worker. | A 6-session, grade-specific digital citizenship curriculum provided to youth-caregiver dyads by a community health worker, focused on skills and knowledge for safe and healthy digital engagement. |
| Role in trial | Primary investigational arm evaluating a resilience and self-regulation program for youth with significant risk factors and their caregivers. | Active comparison group receiving structured digital safety curriculum, intended to control for attention and contact with a health worker. |
| Primary use or purpose | To reduce risk factors for substance use and improve emotional regulation by building resilience and self-regulation capacities in high-risk adolescents and their caregivers. | To serve as an active attention control, offering youth-caregiver dyads practical skills and education on digital engagement and online safety. |
| How it is given or performed | Delivered as 6 weekly group sessions by a community health worker, involving psychoeducation, coaching, and HRV biofeedback for dyad participants. | Provided via 6 weekly sessions by a community health worker, focusing on digital citizenship skills by grade level to youth and caregiver dyads. |
| Evidence status/maturity | The GRIT intervention is currently being evaluated in a randomized trial; external literature on similar family-based, resilience-focused programs shows potential benefit in reducing risk for substance use, improving self-regulation, and supporting family functioning in high-risk adolescents. | Digital literacy and citizenship curricula can increase awareness and some behavioral skills, but do not directly target resilience or emotional regulation; no evidence that DCC alone reduces risk for substance use in high-risk youth. |
| Important limitations | GRIT requires active engagement from both youth and caregivers, multiple in-person sessions, and may face implementation barriers in some communities; evidence of effectiveness is not yet established in this population. | DCC may not sufficiently address the underlying psychosocial or emotional regulation needs of high-risk youth, serving primarily as an active attention control rather than a targeted prevention strategy. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants receive 6 weekly sessions of either the GRIT intervention, which includes supportive health coaching and self-regulation techniques, or the Digital Citizenship Curriculum focusing on navigating the digital world.
Weekly visits for 6 weeks (in-person or virtual)
Duration - 12 months
Participants are followed for up to 12 months after the intervention to assess substance use initiation, emotional regulation, and other health outcomes.
3 visits at immediately after intervention, 6 months, and 12 months post-intervention
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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https://pubmed.ncbi.nlm.nih.gov/24278819/University of California, Irvine
Lead Sponsor
University of California, Los Angeles
Collaborating Sponsor