Prospective Randomized Multicenter Trial Comparing the Safety and Efficacy of Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA) Versus Anterior Cervical Thyroidectomy (AC)

What this Trial Is About

Researchers are evaluating the Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA) compared to the traditional Anterior Cervical thyroidectomy (AC) in patients needing lobectomy or total thyroidectomy without lymph node procedures. This study aims to assess whether TOETVA, a newer surgical technique avoiding neck scars, is as safe and effective as the standard AC method. The trial focuses on early and mid-term postoperative complications, quality of life, and pain levels after surgery. The study involves two groups: one receiving the TOETVA procedure and the other undergoing the AC surgery. TOETVA uses an endoscopic approach through the mouth to access the thyroid gland, potentially reducing visible scarring and tissue dissection. The AC procedure is the conventional open surgery with a neck incision. The trial will compare outcomes such as complication rates and patient recovery between these two surgical methods. Participants will be monitored for complications during the first 24 hours and up to 30 days after surgery. Quality of life and pain will be assessed at one month and six months post-operation using validated measures. The study includes follow-up visits to evaluate healing and patient well-being. Participation lasts through the surgical treatment and follow-up assessments, ensuring thorough evaluation of both surgical techniques.

TOETVA Technique Compared With Anterior Cervical Thyroidectomy (AC) in Terms of Efficacy and Safety