Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
FEMALE
NCT07052266

Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Led by Weill Medical College of Cornell University · Updated on 2025-12-26

550

Participants Needed

5

Research Sites

169 weeks

Total Duration

On this page

Sponsors

W

Weill Medical College of Cornell University

Lead Sponsor

M

Myriad Genetics, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention and be cost-effective, especially among underserved populations.

CONDITIONS

Official Title

Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Who Can Participate

Age: 18Years - 55Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years - 55 years
  • Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site
  • Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider
  • Patients with prior OCS but planned to repeat OCS are eligible
  • Patients can speak and read in English or Spanish
Not Eligible

You will not qualify if you...

  • Patients who have previously completed a multigene hereditary cancer syndrome panel
  • Patients who have a hematologic cancer or hematologic pre-cancer
  • Patients who have a history of an autologous bone marrow transplant

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Trial Site Locations

Total: 5 locations

1

Reproductive Medicine

Brooklyn, New York, United States, 11201

Actively Recruiting

2

NewYork-Presbyterian Weill Cornell Medicine

Brooklyn, New York, United States, 11215

Not Yet Recruiting

3

Reproductive Medicine

New York, New York, United States, 10021

Actively Recruiting

4

Weill Cornell Medicine

New York, New York, United States, 10065

Actively Recruiting

5

NewYork-Presbyterian Weill Cornell Medicine Queens

Queens, New York, United States, 11355

Actively Recruiting

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Research Team

S

Steve Lopez, BA

CONTACT

R

Ravi Sharaf, MD, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

2

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