Actively Recruiting

All Genders
NCT04239703

Trifecta-Kidney cfDNA-MMDx Study

Led by University of Alberta · Updated on 2026-03-18

300

Participants Needed

31

Research Sites

417 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

N

Natera, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscope® (MMDx) Diagnostic System results in indication biopsies.

CONDITIONS

Official Title

Trifecta-Kidney cfDNA-MMDx Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All kidney transplant recipients undergoing a kidney biopsy for clinical indications, as determined by their physician or surgeon, will be eligible to enroll in the study.
Not Eligible

You will not qualify if you...

  • Patients who decline participation or are unable to give informed consent
  • Recipients of multiple organ transplants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 31 locations

1

Tampa General Hospital

Tampa, Florida, United States, 33606

Actively Recruiting

2

University of Maryland School of Medicine

Baltimore, Maryland, United States, 21201

Actively Recruiting

3

The Johns Hopkins University, School of Medicine

Baltimore, Maryland, United States, 21205

Actively Recruiting

4

Detroit Medical Center, Harper University Hospital of Wayne State University

Detroit, Michigan, United States, 48201

Not Yet Recruiting

5

Henry Ford Hospital

Detroit, Michigan, United States, 48202

Actively Recruiting

6

Barnes-Jewish Hospital, Washington University at St. Louis

St Louis, Missouri, United States, 63110

Actively Recruiting

7

University Hospitals Cleveland Medical Ctr.

Cleveland, Ohio, United States, 44106-5048

Actively Recruiting

8

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Actively Recruiting

9

Intermountain Transplant Services

Murray, Utah, United States, 84107

Actively Recruiting

10

Virginia Commonwealth University Medical Center

Richmond, Virginia, United States, 23298

Actively Recruiting

11

Division of Nephrology & UW Organ Transplant Center University of Washington

Seattle, Washington, United States, 98195

Actively Recruiting

12

Department of Nephrology, The Royal Melbourne Hospital 1 South East

Melbourne, Australia, VIC 3050

Actively Recruiting

13

University of Alberta, Department of Medicine

Edmonton, Alberta, Canada, T6G 2G3

Actively Recruiting

14

ST. Paul's Hospital, 6A Providence Building, 1081 Burrard Street

Vancouver, British Columbia, Canada, V6Z 1Y6

Actively Recruiting

15

University Hospital Merkur Renal Division

Zagreb, Croatia, 1910000

Actively Recruiting

16

Institute for Clinical and Experimental Medicine (IKEM)

Prague, Czechia, 140 21 Praha 4

Actively Recruiting

17

Charite-Medical University of Berlin Department of Nephrology

Berlin, Germany, 10117

Actively Recruiting

18

Centre of Nephrology, Vilnius University Hospital Santaros Klinikos

Vilnius, Lithuania, LT-08661

Actively Recruiting

19

Department of Nephrology and Transplantation Medical University in Bialystok

Bialystok, Poland, 15-540

Completed

20

University Hospital nr1 Bydgoszcz, Klinika Transplantologii

Bydgoszcz, Poland, 85-094

Completed

21

Medical University of Gdańsk Klinika Nefrologii Transplantologii i Chorób Wewnętrznych

Gdansk, Poland, 80-259

Actively Recruiting

22

Medical University of Silesia

Katowice, Poland, 40-027

Actively Recruiting

23

Department of Transplantation and General Surgery, Wojewodzki Hospital

Poznan, Poland, 60-479

Actively Recruiting

24

Department of Nephrology, Transplantation and Internal Medicine, University Hospital n.2

Szczecin, Poland, 70-111

Actively Recruiting

25

Pomeranian Medical University, Samodzielny Publiczny Woj. Szpital Zespolony, Oddzial Nefrologii i Transplantacji Nerek

Szczecin, Poland, 71-455

Actively Recruiting

26

Medical University of Warsaw, Department of Transplantation Medicine, Nephrology and Internal Diseases

Warsaw, Poland, 02-006

Actively Recruiting

27

Transplant Medicine & Nephrology Clinic, Medical University of Warsaw

Warsaw, Poland, 02-006

Actively Recruiting

28

The Children's Memorial Health Institute, Department of Nephrology, Kidney Transplantation and Hypertension

Warsaw, Poland, 04-730

Completed

29

Wroclaw Medical University, Department of Nephrology and Transplantation Medicine

Wroclaw, Poland, 50-556

Actively Recruiting

30

Department of Nephrology, University Medical Centre

Ljubljana, Slovenia, 21000

Actively Recruiting

31

University Hospital Zurich

Zurich, Switzerland, 8091

Completed

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Research Team

K

Konrad S Famulski, PhD

CONTACT

R

Robert Polakowski, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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