Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06336941

"Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON)

Led by University of Pisa · Updated on 2026-02-25

400

Participants Needed

1

Research Sites

655 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Oral diseases are currently diagnosed by means of clinical examination and supported by surgical biopsy procedures. In particular, daily oral medicine practice is lacking the use of a routine diagnostic support to the visualization of anatomical structures located beyond the mucosal surface. Considering the growing interest in minimally invasive diagnosis, the possibility of having an imaging technique dedicated to the investigation of oral soft tissues and their alterations may be instrumental to support the clinical diagnosis. Therefore, attempts to introduce conventional ultrasonography (US) to the diagnostic work-up of pathological conditions of the head and neck have been done, exploiting the unique features of this technique in terms of limited invasive- ness, repeatability, and cost efficiency. In the literature, both extraoral and intraoral applications of US have been reported. Extraoral applications mainly focus on the characterization of oral and maxillofacial swellings of various origin, while intraoral applications mostly involve the study of malignant lesions in terms of tumor thickness and depth of invasion. The aim of the present protocol is to evaluate the role of intraoral ultra-high frequency ultrasonography in the study of oral mucosal lesions.

CONDITIONS

Official Title

"Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of oral squamous cell carcinoma
  • Eligibility for surgical treatment
  • Acceptance to be included in the study
Not Eligible

You will not qualify if you...

  • Oral lesions other than oral squamous cell carcinoma
  • Pregnant or breastfeeding patients
  • Uncontrolled chronic diseases and/or conditions hindering the participation in the study
  • Denial of inclusion in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Università di Pisa

Pisa, Italy, 56126

Actively Recruiting

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Research Team

R

Rossana Izzetti, DDS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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"Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON) | DecenTrialz