Ultrasound Study to Detect Body Composition Changes in Critically Ill Obstetrics and Gynecology Patients and Their Link to Clinical Outcomes

What this Trial Is About

Critically ill patients, especially those in obstetrics and gynecology, are vulnerable to muscle loss and fluid changes that can negatively affect their recovery and clinical outcomes. Accurate assessment of body composition in hospital settings remains challenging, making ultrasound a promising tool due to its portability, bedside use, and radiation-free nature. This research investigates ultrasounds role in detecting changes in body composition and correlating these changes with clinical outcomes in critically ill obstetrics and gynecological patients. The study uses ultrasound to measure muscle mass, fat thickness, and extracellular edema at multiple body sites, including the quadriceps and bicep, following a standardized five-site protocol. Assessments are performed starting at admission and repeated every two days for up to 20 days or until discharge or death. Muscle quality is graded by visibility of muscle fascia and bone surface, while edema is evaluated using a five-point scale. This is an observational study focusing on critically ill female patients admitted to obstetrics and gynecology intensive care units. Participants undergo body composition assessments with ultrasound on admission and every two days thereafter. Researchers monitor changes in muscle, fat, and fluid elements and correlate these with clinical outcomes such as mortality, need for ventilatory or circulatory support, or prolonged ICU stay. The study provides non-invasive monitoring to guide nutrition and physical therapy in critical care. The total observation period per participant is up to 20 days from admission, with ongoing evaluation of body composition changes and clinical status.

Ultrasound Detection of Body Composition in Critical Care