Ultrasound Evaluation of the Myometrium Using the MUSA Terminology, Comparison With Histology

What this Trial Is About

This research aims to evaluate how accurately the MUSA terms and definitions can diagnose different types of myometrial lesions larger than 1 cm, such as benign fibroids, adenomyomas, or malignant uterine sarcomas. The study also seeks to develop a prediction model to distinguish between benign and malignant myometrial lesions based on selected ultrasound characteristics. The evaluation is supported by prior data estimating a 4.9% incidence of uterine sarcomas in women with myometrial lesions. Patients scheduled for hysterectomy due to myometrial pathology will undergo a detailed preoperative ultrasound scan assessing about 50 ultrasound features. The study includes various types of hysterectomy procedures, such as vaginal, total abdominal, laparoscopic, or robotic hysterectomy, ensuring the uterus is removed intact. In cases where surgery is not possible, a representative biopsy may be performed if justified by oncology specialists. Participants will be closely monitored through ultrasound assessments before their surgery, with researchers measuring the diagnostic accuracy of MUSA terms. The main outcome is to evaluate how well these ultrasound definitions identify lesion types over a four-year period. Additionally, the development of a predictive model based on specific ultrasound features will be studied over five years. The study tracks patient histology results post-surgery and aims to improve diagnosis and treatment planning for myometrial lesions.

Ultrasound Evaluation of the Myometrium Using the MUSA Terminology Comparison With Histology