The current use of ultrasound to measure skeletal muscle and its ability to predict clinical outcomes: a systematic review.
Patrick Casey, Mohamed Alasmar, John McLaughlin...
https://pubmed.ncbi.nlm.nih.gov/35851996Actively Recruiting
Led by Osijek University Hospital · Updated on 2026-05-29
50
Participants Needed
1
Research Sites
4 weeks
Total Duration
This observational study focuses on surgical patients in the intensive care unit (ICU) to evaluate ultrasound indicators of nutritional status and how these relate to treatment outcomes. Researchers aim to better understand how factors like muscle thickness and frailty affect ICU treatment duration and patient recovery. The study acknowledges that nutritional status and frailty, especially in older or critically ill patients, are important predictors of ICU outcomes and resource use. Patients admitted to the surgical ICU will be observed, with ultrasound measurements taken of thigh muscles and surrounding fat tissue within 48 hours of ICU admission. The study will record muscle thickness and echogenicity using ultrasound imaging software, along with clinical assessments like the Clinical Frailty Scale and nutritional risk screening. Laboratory tests including hemoglobin, albumin, lactate, and C-reactive protein levels will also be collected to complement the ultrasound data. Participants will have demographic and clinical data recorded from medical records, including age, gender, comorbidities, and ICU stay details. Frailty will be assessed through interviews with patients or family members. The study will monitor outcomes such as muscle measurements, nutritional scores, length of mechanical ventilation, and blood test results to explore relationships between nutritional status and recovery in ICU patients. The total study duration extends up to one month for ventilation length assessment.
CONDITIONS
Ultrasound, Nutritional Status, and Outcomes in Surgical ICU
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for informed consent and eligibility assessment
Duration - Within 48 hours of admission
Participants undergo ultrasound examination of thigh muscles and laboratory tests to assess nutritional status and frailty within 48 hours of ICU admission.
1 visit (in-person) for ultrasound and blood sampling
Duration - Up to 1 month from ICU admission
Participants are monitored during their stay in the intensive care unit for clinical outcomes including duration of mechanical ventilation and ICU treatment.
Ongoing monitoring during ICU stay; assessments based on routine care
Total: 1 location
1
Osijek University Hospital; Medical Faculty
Osijek, Croatia, 31000
Actively Recruiting
S
Slavica Kvolik, prof.
S
Stjepan Juric, Prof
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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