Actively Recruiting
Ultrasonic Imaging of Bone Graft Healing in Extraction Sockets for Precise and Personalized Implant Therapy
Led by University of Michigan · Updated on 2025-10-31
140
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute of Dental and Craniofacial Research (NIDCR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research investigates the healing process of bone grafts in dental extraction sockets using ultrasound compared with micro-CT/LASCA imaging. The study involves patients who need a hopeless tooth removed, followed by bone grafting and planned dental implant surgery. It aims to gather detailed information on graft maturation, which could help in early detection of graft failure or guide clinical decisions like infection management. Participants will be scanned with ultrasound and LASCA at multiple points: before tooth extraction, at the time of extraction and bone graft placement, and during follow-ups at 2 weeks, 1 month, 2 months, and 3 months post-surgery. These evaluations include clinical exams and measurements alongside the imaging to monitor recovery and bone healing progression. Throughout the study, researchers will assess the healing status of the bone graft using various diagnostic tools over approximately six months. Participants will undergo scheduled check-ups and scans to track graft maturation and recovery. The study is observational, aiming to collect valuable data without altering standard treatment, with a total participation period around six months.
CONDITIONS
Brief Title
Ultrasound for Socket Healing Evaluation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients at least 18 years of age
- Have at least one tooth that is considered hopeless and planned for extraction
- Planned for a bone grafting procedure followed by dental implant surgery
You will not qualify if you...
- Patients not willing or not able to have an extraction, bone graft, and subsequent implant surgery due to health, finance, or other reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 pre-assessment visit (in-person)
Duration - 1 day
Participants undergo ultrasound and LASCA scanning along with clinical exams and measurements on the day of tooth extraction and socket augmentation.
1 visit on the day of tooth extraction and graft placement (in-person)
Duration - Approximately 3 months
Participants are monitored during recovery with checkups to assess graft maturation and healing after surgery.
Checkups at 2 weeks, 1 month, 2 months, and 3 months post-surgery (4 visits, in-person)
Trial Site Locations
Total: 1 location
1
Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
O
Oliver Kripfgans, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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