Study of Collagen Membrane Use to Protect Jawbone After Tooth Extraction for Future Dental Implants

What this Trial Is About

Researchers are evaluating whether adding a resorbable collagen membrane to an anorganic bone-collagen composite ABCC graft improves the preservation of jawbone shape and volume after tooth extraction, which is important for future dental implant placement. This randomized controlled trial compares two approaches in adults needing extraction of a single-rooted maxillary tooth with significant buccal bone loss. The study aims to assess healing outcomes and patient satisfaction over a four-month period. Participants will be randomly assigned to one of two groups one receiving the ABCC graft alone covered by a collagen sponge, and the other receiving the ABCC graft combined with a resorbable collagen membrane placed in a buccal pouch alongside the graft. Both groups will have similar minimally invasive tooth extraction and follow-up care. The collagen membrane is used to replace missing buccal bone and contain the graft material. During the study, participants will undergo three-dimensional cone beam computed tomography CBCT scans, digital intraoral scans, and clinical evaluations to measure changes in bone and soft tissue. Healing will be monitored for complications like wound issues or infections, and patient-reported outcomes such as pain and satisfaction will be collected. In some participants, bone samples will be analyzed at implant placement to study bone healing. The study will determine if treatment allows implant placement without additional bone grafting, with total evaluation lasting about four months.

Effect of Collagen Membrane on Ridge Preservation