Actively Recruiting
Understanding the Transition from Normal Melanocytes to Nevus to Melanoma
Led by Fundacion Clinic per a la Recerca Biomédica · Updated on 2025-02-27
100
Participants Needed
2
Research Sites
152 weeks
Total Duration
On this page
Sponsors
F
Fundacion Clinic per a la Recerca Biomédica
Lead Sponsor
I
Institut National de la Santé Et de la Recherche Médicale, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L/GCMN. The secondary objectives are: * To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients. * To improve the early diagnosis and treatments for intermediate conditions such as L/GCMN through evidence-based interpretation of personal risk from endogenous or exogenous sources. * To test pre-clinical strategies to best model and improve patient response.
CONDITIONS
Official Title
Understanding the Transition from Normal Melanocytes to Nevus to Melanoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a congenital nevus estimated to be 20 cm or larger
- Be over 18 years of age
You will not qualify if you...
- No available biological material
- Have not signed the informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
French National Institute of Health and Medical Research
Marseille, France
Actively Recruiting
2
Hospital Clínic de Barcelona (Dermatology service)
Barcelona, Spain
Actively Recruiting
Research Team
S
Susana Puig Sardà, MD, PhD
CONTACT
A
Adrián López Canosa, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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