Should a Urinary Tract Infection Be Treated before a Total Joint Arthroplasty?
Javad Parvizi, Kyung-Hoi Koo
https://pubmed.ncbi.nlm.nih.gov/30899708Actively Recruiting
Led by Tomas Bata Hospital, Czech Republic · Updated on 2025-07-08
80
Participants Needed
1
Research Sites
13 weeks
Total Duration
Researchers are observing seniors aged 65 and older who are undergoing surgical procedures related to bone surgery, traumatology, or orthopedics. The study aims to understand the relationship between urinary tract infections or colonization before surgery (within 30 days prior) and the occurrence of specific postoperative complications during hospitalization. The study also explores the role of frailty and antibiotic use before surgery in these outcomes. Before surgery, patients will have urine samples collected and tested for infection through chemical and sediment examinations as part of their pre-anesthetic checkup. If infection is suspected, further bacteriological tests will be done. Information such as symptoms, fever presence, treatment of any infection, type of anesthesia, antibiotic use, and patient origin (home or care facility) will be recorded. After surgery, researchers will monitor for urinary infections and complications including fever, circulatory instability, delirium, sepsis, infection, and death while tracking hospital stay and departments involved. Participants will be followed during their hospital stay with assessments including urine tests, symptom tracking, antibiotic therapy, and frailty evaluation using the Clinical Frailty Scale. Researchers will review these data to identify connections between preoperative urinary infections and postoperative complications, as well as the impact of frailty and antibiotic treatments. The study will monitor outcomes for about one week after surgery, with detailed recording of complications and treatments throughout hospitalization.
CONDITIONS
Urinary Infection and Colonization in Bone Procedures
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) before surgery for urine examination and clinical assessment
Duration - Hospitalization period following surgery
Participants undergo bone surgery and are monitored during their hospitalization for postoperative complications such as fever, circulatory instability, infection, sepsis, delirium, and antibiotic use.
Monitoring visits during hospital stay
Duration - Up to 1 week after surgery
Participants' postoperative complications and recovery trajectory are assessed up to one week after surgery.
Follow-up assessments during hospitalization and up to one week post-surgery
Total: 1 location
1
Tomas Bata Hospital
Zlín, Czechia, 76001
Actively Recruiting
K
Klára Nekvindová, M.D., Ph.D.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Javad Parvizi, Kyung-Hoi Koo
https://pubmed.ncbi.nlm.nih.gov/30899708