Actively Recruiting

Age: 65Years +
All Genders
ID06896643

Urinary Infection and Colonization in Bone Procedures in Seniors Aged 65 and Over

Led by Tomas Bata Hospital, Czech Republic · Updated on 2025-07-08

80

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are observing seniors aged 65 and older who are undergoing surgical procedures related to bone surgery, traumatology, or orthopedics. The study aims to understand the relationship between urinary tract infections or colonization before surgery (within 30 days prior) and the occurrence of specific postoperative complications during hospitalization. The study also explores the role of frailty and antibiotic use before surgery in these outcomes. Before surgery, patients will have urine samples collected and tested for infection through chemical and sediment examinations as part of their pre-anesthetic checkup. If infection is suspected, further bacteriological tests will be done. Information such as symptoms, fever presence, treatment of any infection, type of anesthesia, antibiotic use, and patient origin (home or care facility) will be recorded. After surgery, researchers will monitor for urinary infections and complications including fever, circulatory instability, delirium, sepsis, infection, and death while tracking hospital stay and departments involved. Participants will be followed during their hospital stay with assessments including urine tests, symptom tracking, antibiotic therapy, and frailty evaluation using the Clinical Frailty Scale. Researchers will review these data to identify connections between preoperative urinary infections and postoperative complications, as well as the impact of frailty and antibiotic treatments. The study will monitor outcomes for about one week after surgery, with detailed recording of complications and treatments throughout hospitalization.

CONDITIONS

Brief Title

Urinary Infection and Colonization in Bone Procedures

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 65 years, including
  • Undergoing elective or acute trauma/orthopedic bone surgery
  • Urine examination including chemical analysis and sediment as part of pre-anesthetic evaluation
  • Signed informed consent for participation in the research
Not Eligible

You will not qualify if you...

  • Negative urine findings in chemical examination and sediment before surgery
  • Influence of premedication, alcohol, or drugs at time of evaluation
  • Sensory impairment such as blindness
  • Preoperative delirium
  • Severe mental disorder
  • Sopor or coma
  • Septic state
  • Acute respiratory failure
  • Refusal to participate in the study

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) before surgery for urine examination and clinical assessment

Surgery and Immediate Post-operative Care

Duration - Hospitalization period following surgery

Participants undergo bone surgery and are monitored during their hospitalization for postoperative complications such as fever, circulatory instability, infection, sepsis, delirium, and antibiotic use.

Monitoring visits during hospital stay

Post-operative Follow-up

Duration - Up to 1 week after surgery

Participants' postoperative complications and recovery trajectory are assessed up to one week after surgery.

Follow-up assessments during hospitalization and up to one week post-surgery

Trial Site Locations

Total: 1 location

1

Tomas Bata Hospital

Zlín, Czechia, 76001

Actively Recruiting

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Research Team

K

Klára Nekvindová, M.D., Ph.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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