Actively Recruiting

Age: 18Years +
All Genders
NCT03909139

Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral Tear

Led by Massachusetts General Hospital · Updated on 2025-10-27

400

Participants Needed

1

Research Sites

407 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Femoro-acetabular impingement is a well known cause of damage to the acetabular labrum and chondrolabral junction. Additionally, it has been proposed that disruption of hip biomechanics resulting from a labral tear causes a faster progression towards osteoarthritis (OA). This progression has been observed to begin with breakdown of the chondrolabral junction with later development of diffuse osteoarthritis. Use of hip arthroscopy has increased dramatically in recent years to treat symptomatic labral tears and potentially avoid the morbidity and cost associated with hip osteoarthritis. Correction of labral pathology presents a technical challenge and many techniques currently exist. Increased understanding of the structure-functional relationship dictated by labral anatomy has led to the development of methods aimed at restoring functional anatomy by re-establishing the labrum's native position and contour on the rim of the acetabulum. Therefore, akin to repairing a torn meniscus in the knee, restoring the anatomic footprint of a torn labrum will reconstitute normal joint biomechanics. Despite the advances in techniques for labral repair, strategies for mitigating or repairing damage to the chondrolabral junction do not yet exist. This area has been shown to consist of hyaline and fibro cartilage. Many techniques for cartilage repair exist, although most are not feasible due to technical challenges specific to the hip joint. The management of articular cartilage defects is one of the most challenging clinical problems for orthopaedic surgeons. Articular cartilage has a limited intrinsic healing capacity, and pathology frequently results in gradual tissue deterioration. Currently, the standard surgical intervention for end-stage degenerative joint pathology is total joint replacement. Early surgical interventions for symptomatic cartilage lesions including cell based therapies such as autologous chondrocyte implantation (ACI), bone marrow aspirate concentrate (BMAC) implantation, or microfracture have been suggested to restore normal joint congruity and minimize further joint deterioration. Techniques such as ACI, which have been successfully used in the knee joint, have limited application in the hip due to the technical difficulties of open procedures.

CONDITIONS

Official Title

Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral Tear

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Symptoms consistent with acetabular labrum tear such as catching, clicking, popping, or hip pain
  • Symptoms not caused by other acute hip conditions like infection, fractures, or other syndromes
  • Availability of hip X-rays and MRI or MRA imaging
  • Evidence of labral tear on MRI or MRA
  • Ability and willingness to understand and sign informed consent
  • Returning subjects enrolled in protocol 2017P001391/PHS
Not Eligible

You will not qualify if you...

  • Non-English speaking individuals
  • Presence of systemic infection
  • Use of systemic heparinization (blood thinning medication)
  • Pregnant women or fetuses

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

MGH, Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

S

Scott D Martin, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral Tear | DecenTrialz