Actively Recruiting

Phase Not Applicable
Age: 50Years - 65Years
All Genders
Healthy Volunteers
NCT05541887

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Led by University of Florida · Updated on 2025-06-12

25

Participants Needed

1

Research Sites

169 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities

CONDITIONS

Official Title

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Who Can Participate

Age: 50Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy
  • BMI between 18.5 and 29.9
  • Body weight at least 110 pounds
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Breast-feeding
  • Smoking
  • Diabetes
  • Heavy alcohol use
  • Subjective cognitive impairment without clinical diagnosis (Montreal cognitive assessment score under 26)
  • Inability to understand cognitive tasks
  • Use of medications that may affect study outcomes (e.g., psychostimulants)
  • Cannabis use
  • Diagnosed mental illnesses
  • Cardiovascular disorders
  • Neurological disorders
  • Uncontrolled high blood pressure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Food Science and human nutrition department at University of Florida

Gainesville, Florida, United States, 32611

Actively Recruiting

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Research Team

K

Kylee Mai

CONTACT

L

Liwei Gu, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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