Actively Recruiting

Phase Not Applicable
Age: 18Months - 30Months
All Genders
Healthy Volunteers
NCT06156865

Using Neuroimaging and Behavioral Assessments to Understand Late Talking

Led by University of Toronto · Updated on 2025-05-11

45

Participants Needed

2

Research Sites

75 weeks

Total Duration

On this page

Sponsors

U

University of Toronto

Lead Sponsor

H

Holland Bloorview Kids Rehabilitation Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder. While effective and early interventions can mitigate the impact of late talking, not enough is known about its neural basis, yet is needed to inform the design of more individualized interventions. This proposed effort uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie learning and late talking, while also considering their association to treatment-related changes in LT.

CONDITIONS

Official Title

Using Neuroimaging and Behavioral Assessments to Understand Late Talking

Who Can Participate

Age: 18Months - 30Months
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Child and parent are primarily monolingual/native English speakers
  • Child is enrolled at one of the participating facilities
  • Child is recruited via word of mouth, including social media
  • Child is between 18 and 30 months of age
  • Child does not have any contraindications to magnetic resonance imaging (e.g., intracranial metal implants, claustrophobia)
  • Child does not have any uncorrected vision challenges
Not Eligible

You will not qualify if you...

  • Child does not meet criteria for late talking or typical development
  • Standard magnetic resonance imaging exclusion criteria
  • Gestational age less than 37 weeks or greater than 42 weeks
  • Child is placed in special education based on ability or behavior

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Grandview Kids

Oshawa, Ontario, Canada, L1H0C8

Not Yet Recruiting

2

Speech Specialists

Toronto, Ontario, Canada, M1X0C3

Actively Recruiting

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Research Team

K

Karla N Washington, PhD

CONTACT

N

Nicole Bazzocchi, MhSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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