Actively Recruiting

Age: 25Years - 70Years
FEMALE
Healthy Volunteers
NCT05640700

Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia

Led by Hadassah Medical Organization · Updated on 2025-03-19

90

Participants Needed

1

Research Sites

163 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.

CONDITIONS

Official Title

Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia

Who Can Participate

Age: 25Years - 70Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 25-70
  • Attended the clinic for a Pap smear or colposcopy
Not Eligible

You will not qualify if you...

  • Patient does not approve sample collection
  • Usage of antibiotics in the month prior to clinic visit
  • Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.)
  • Menstruation
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hadassah Medical Center

Jerusalem, Israel

Actively Recruiting

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Research Team

A

Ahinoam Lev Sagie, MD

CONTACT

L

Lilah Tsaitlin Mor, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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