Actively Recruiting
Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection
Led by Northern Jiangsu People's Hospital · Updated on 2026-04-01
15
Participants Needed
2
Research Sites
53 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.
CONDITIONS
Official Title
Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- A clinical, radiological or histologic diagnosis of cirrhosis of any cause
- Splenomegaly with secondary hypersplenism
- Portal hypertension with bleeding
- No portal vein thrombosis as shown by ultrasound and angio-CT
- Signed informed consent to join the study
You will not qualify if you...
- Delayed gastric emptying
- Diarrhea
- Liver cancer or any other cancer
- Hypercoagulable state not related to liver disease
- Use of oral contraceptives, anticoagulants, or anti-platelet drugs
- Child-Pugh class C liver disease
- Recent peptic ulcer disease
- History of hemorrhagic stroke
- Pregnancy
- Uncontrolled high blood pressure
- HIV infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Clinical Medical College of Yangzhou University
Yangzhou, Jiangsu, China, 225001
Actively Recruiting
2
Clinical Medical College, Yangzhou University
Yangzhou, Jiangsu, China, 225001
Completed
Research Team
G
Guo-Qing Jiang, MD
CONTACT
D
Dou-sheng Bai, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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