Actively Recruiting

Phase Not Applicable
Age: 5Months - 5Months
All Genders
NCT07081698

Walnuts as an Infant Solid Food for Health

Led by Colorado State University · Updated on 2025-07-23

90

Participants Needed

1

Research Sites

136 weeks

Total Duration

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Sponsors

C

Colorado State University

Lead Sponsor

C

California Walnut Commission

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective is to investigate the effect of walnuts on gut microbiota, inflammatory markers, atopic dermatitis status, and indices of allergy outcomes in breastfed infants during early complementary feeding. The three primary aims include: Aim 1: Evaluate the effect of walnut consumption on gut microbiota structure and function, inflammation, atopic dermatitis, and allergy outcomes. Aim 2: Evaluate the impact of walnut consumption on infant growth trajectories and risk of overweight. Aim 3 (exploratory): Identify walnut-specific food signatures that are associated with gut microbiota and immunity biomarkers using a novel nutri-metabolomics technique.

CONDITIONS

Official Title

Walnuts as an Infant Solid Food for Health

Who Can Participate

Age: 5Months - 5Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Full term: gestational age 237 weeks
  • Generally healthy without conditions that would affect normal growth
  • No significant consumption of complementary food (e.g., no more than 1 oz of solid foods per week)
  • Exclusively breastfed (< 2 weeks of cumulative formula exposure)
Not Eligible

You will not qualify if you...

  • Adults unable to consent
  • Pregnant women
  • Prisoners

AI-Screening

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Trial Site Locations

Total: 1 location

1

Food Science and Human Nutrition Clinical Research Laboratory

Fort Collins, Colorado, United States, 80523

Actively Recruiting

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Research Team

N

Nathan Campbell, MS

CONTACT

K

Kinzie Matzeller, MS RDNCLC

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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