Actively Recruiting

All Genders
ID02762175

3D Volumetric Changes in the Upper Airway After Maxillomandibular Advancement in Obstructive Sleep Apnea Syndrome Patients and the Implication on Quality of Life: A Prospective Registry

Led by AZ Sint-Jan AV · Updated on 2022-02-28

150

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying obstructive sleep apnea syndrome (OSAS), a sleep disorder marked by loud snoring and repeated airway blockages during sleep that cause daytime tiredness. This observational study aims to create a prospective database to track changes in the upper airway volume and anatomy after maxillomandibular advancement (MMA) surgery, along with measuring the apnea-hypopnea index (AHI) and patients' quality of life. The study collects detailed data on patient demographics, virtual 3D cone-beam CT (CBCT) surgical planning, orthognathic surgery details, sleep study results, and quality of life assessments as part of routine care.

CONDITIONS

Brief Title

3D Volumetric Changes in the Upper Airway After MMA in OSAS Patients and the Implication on QOL: A Prospective Registry

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of all ages
  • Patients of all genders
  • Patients diagnosed with OSAS, based on an AHI 25 5
  • All consecutive OSAS patients operated by N. Neyt from January 2015 onwards
Not Eligible

You will not qualify if you...

  • Patients not eligible according to abovementioned criteria
  • Patients with morbid obesity (BMI >35), if judged non-eligible by the treating surgeon

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to 1 week

Participants undergo maxillomandibular advancement surgery and receive immediate post-operative care.

1 hospital stay with immediate post-operative monitoring

Post-operative Follow-up

Duration - 4 to 12 months

Participants are monitored to assess 3D volumetric changes of the upper airway and quality of life after surgery.

Multiple visits including imaging and questionnaire assessments over 4 to 12 months

Trial Site Locations

Total: 1 location

1

Division of Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge Oostende AV

Bruges, Belgium

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Research Team

A

Araceli Diez-Fraile, MSc, PhD, VMD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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