Actively Recruiting
Study of Sex Differences in Blood Pressure Control in Adults with Untreated Obstructive Sleep Apnea
Led by Mayo Clinic · Updated on 2026-01-07
60
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating how men and women with untreated obstructive sleep apnea OSA may differ in how their nervous system controls blood pressure. This observational study aims to understand sex differences in neurocirculatory regulation among adults aged 20 to 70 with OSA. The trial is sponsored by Mayo Clinic and focuses on baseline measurements of blood pressure, arterial stiffness, and endothelial function. Participants will be observed without receiving any study treatments or interventions. The study measures include sympathetic nerve activity parameters such as burst frequency, incidence, amplitude, and total muscle sympathetic nerve activity. There are no specified treatment groups or placebo comparisons since this is an observational study. During the study, participants will undergo assessments to measure blood pressure and vascular function as well as detailed evaluations of nerve activity controlling circulation. These tests occur at baseline to gather initial data. The study will monitor participants for any changes and aims to complete data collection by March 2027. Participants usual care continues alongside their involvement in this research.
CONDITIONS
Brief Title
A Study of Sex Differences in Neurocirculatory Control
Research Team
J
Joshua Bock, PhD
I
Ian Greenlund, PhD
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