Actively Recruiting

Phase Not Applicable
Age: 40Years - 85Years
MALE
NCT04951817

68Ga-PSMA PET/CT for Ra223 Assessment

Led by Chang Gung Memorial Hospital · Updated on 2025-08-29

52

Participants Needed

1

Research Sites

182 weeks

Total Duration

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AI-Summary

What this Trial Is About

Primary objective: i.The primary objective is to compare the diagnostic positivity in progression of 68Ga-PSMA PET and Bone scan. Secondary objectives: i.The correlation between PET osseous tumor burden index and Alk-P level ii.The correlation between PET osseous tumor burden index and PSA level

CONDITIONS

Official Title

68Ga-PSMA PET/CT for Ra223 Assessment

Who Can Participate

Age: 40Years - 85Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male aged 40 to 85 years with life expectancy over 3 months
  • Diagnosed with metastatic castration-resistant prostate cancer (mCRPC) meeting criteria for 223Ra-dichloride use (symptomatic bone metastases, at least two bone metastasis sites, no visceral organ metastasis)
  • Willing to sign informed consent
  • ECOG performance status grade 0 to 2
Not Eligible

You will not qualify if you...

  • Unable to tolerate PET/CT scan due to claustrophobia, inability to lie still, unclear consciousness, or unstable vital signs
  • Renal impairment with glomerular filtration rate below 30 ml/min/1.73 m2 or allergy to contrast medium
  • Significant abnormal lab results (AST or ALT more than three times normal) or high risk for examination after physician evaluation
  • History of other malignancies
  • Grade 3-4 neutropenia (neutrophils less than 1000/uL) or thrombocytopenia (platelets less than 50,000/uL) lasting more than 14 days

AI-Screening

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Trial Site Locations

Total: 1 location

1

Chang Gung Memorial Hospital ,Linkou

Taoyuan City, Taiwan, 333

Actively Recruiting

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Research Team

J

Jing-Ren Tseng, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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