Status:

COMPLETED

Naltrexone for Early Problem Drinkers

Lead Sponsor:

UConn Health

Collaborating Sponsors:

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Conditions:

Alcoholism

Eligibility:

All Genders

18-60 years

Phase:

PHASE4

Brief Summary

Early problem drinkers are prevalent in the United States. Recent controlled trials have shown that brief interventions in the primary care setting can reduce drinking and alcohol-related problems in ...

Eligibility Criteria

Inclusion Criteria:

  • Limited to early problem drinkers (i.e., those with no more than mild alcohol dependence).
  • Have an average weekly alcohol consumption of greater than or equal to 24 standard drinks for men and 18 standard drinks for women.
  • Able to read English at the eighth grade or higher level and show no evidence of significant cognitive impairment.
  • Willing to provide a collateral informant for interviews regarding the patient's drinking during the study.
  • A woman of child-bearing potential must be non-lactating, practicing a reliable method of birth control, and have a negative pregnancy test prior to initiation of treatment.
  • Willing to provide a signed informed consent to participate in the study.

Exclusion Criteria:

  • Have a current clinically significant physical disease or abnormality.
  • Have a serious psychiatric illness.
  • Have a current diagnosis of drug dependence (other than nicotine dependence) or a lifetime diagnosis of opioid dependence.
  • A current diagnosis of alcohol dependence that is moderate or greater in severity or a history of alcohol withdrawal, or recurrent use of alcohol to alleviate alcohol withdrawal symptoms.
  • Used opioids or other psychoactive medications regularly in the month prior to study enrollment.
  • History of hypersensitivity to naltrexone (Revia).

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

September 1 2002

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT00000455

End Date

September 1 2002

Last Update

June 20 2011

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Department of Psychiatry, University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19103

Naltrexone for Early Problem Drinkers | DecenTrialz