Actively Recruiting
Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities
Led by Christiana Care Health Services · Updated on 2025-02-21
12
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
There is no consensus regarding the neurological substrate underpinning ASD. The investigators describe the novel concept of "social reciprocity network" and hypothesize that aberrant connectivity/oscillatory patterns affecting this network contribute to the core deficits in ASD. The overarching goal of this trial is to explore abnormalities involving the neuronal connectivity and oscillatory patterns within the social reciprocity network and to elucidate the role of modulating this network via rTMS in improving the above measures and social cognition in ASD. Quantitative electroencephalography (QEEG) coherence and spectral power analysis are reliable measures of neuronal connectivity and dynamics. The investigators aim to study the QEEG coherence/spectral power analysis to explore the neuronal dynamics affecting the social reciprocity network in ASD.
CONDITIONS
Official Title
Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with autism spectrum disorder (ASD) meeting DSM-V criteria and confirmed by CARS2 or HF
You will not qualify if you...
- Significant anxiety or contact avoidance that prevents cooperation with the procedure
- Known diagnosis of seizures
- Presence of any metal implants or devices in the head or neck area
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Christiana Care
Newark, Delaware, United States, 19718
Actively Recruiting
Research Team
M
Mitra Assadi, MD
CONTACT
R
Ryan Ally, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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