Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06795867

Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine

Led by Brigham and Women's Hospital · Updated on 2025-10-31

40

Participants Needed

1

Research Sites

149 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if the behavioral treatment called Acceptance and Commitment Therapy (ACT) works to improve disability in adults with chronic migraine. The main questions it aims to answer are: Does the use of ACT added to usual treatment improve scores on questionnaires designed to measure daily functioning and activity? Does the use of ACT added to usual treatment improve scores on diaries designed to measure headache frequency and pain? Researchers will compare adding ACT to usual headache treatments to usual headache treatments without ACT. Participants who are selected for ACT will take 8 classes to learn ACT and then will practice it at home, in addition to their regular headache treatment. Those not selected will continue their regular headache treatment. Four times over the following year, participants will answer questions about their symptoms during each of four virtual visits. They will also keep a daily headache diary during the study

CONDITIONS

Official Title

Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willingness and ability to engage in the consent process
  • Willingness to participate in the study, despite randomization outcome
  • Availability for the duration of the study
  • Diagnosis of chronic migraine followed at the Graham Headache Center
  • Access to the necessary resources for participating in a technology-based intervention
Not Eligible

You will not qualify if you...

  • Known major depression or other psychiatric condition
  • Non-English speaking
  • Secondary headache diagnosis
  • Psychotherapy in the prior 18 months
  • Any reason the provider feels would limit participant ability to learn or practice ACT
  • Any previous experience with mindfulness or meditation approaches

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Brigham and Women's / Faulkner Hospital

Boston, Massachusetts, United States, 02130

Actively Recruiting

Loading map...

Research Team

P

Paul Rizzoli, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here