Actively Recruiting
Efficacy of an Asian Culture-tailored Lung Health Intervention on Lung Cancer Screening and Smoking Cessation in Asian Americans
Led by Dana-Farber Cancer Institute · Updated on 2026-03-13
50
Participants Needed
2
Research Sites
4 weeks
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating a counseling and educational program aimed at improving lung health by helping Chinese and Korean American smokers at high risk for lung cancer to quit smoking. This randomized clinical trial compares the effectiveness of the ACT Lung Health Intervention with standard care, focusing on smoking cessation and lung cancer screening behaviors. Participants will be randomly assigned to one of two groups. Group A receives the ACT Lung Health Intervention, which includes eight weekly counseling sessions via phone or video, family coaching, nicotine replacement therapy (patches, gum, lozenges), and educational materials about lung cancer screening with low-dose computed tomography (LDCT). Group B receives standard care with six counseling sessions, nicotine replacement therapy, and educational materials. Both groups undergo assessments at baseline, 1, 3, and 6 months, including saliva tests at 3 and 6 months. Participants will complete questionnaires and saliva tests to monitor smoking abstinence and lung cancer screening completion. The primary outcome is biochemically verified smoking abstinence at 6 months. Secondary outcomes include changes in cigarette consumption, self-reported abstinence at 3 and 6 months, and lung cancer screening completion. The study lasts approximately 6 months and involves about 50 participants, with safety monitored throughout the trial.
CONDITIONS
Brief Title
ACT Lung Health Intervention: Phase Two
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Self-identify as either Chinese or Korean
- Speak Korean, Mandarin, or English
- Are 18 years of age or older
- Are current smokers who have smoked at least 100 cigarettes in their lifetime and smoked at least one cigarette in the last 30 days
- Will live in the United States for the next 12 months
You will not qualify if you...
- Hospitalization for serious mental illness in the past 6 months
- Adults unable to consent
- Adults younger than 50 or older than 80 years
- Individuals who are not adults (infants, children, teenagers)
- Pregnant women
- Prisoners
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote)
Duration - 8 weeks
Participants receive counseling sessions and nicotine replacement therapy to support smoking cessation and learn about lung cancer screening. Counseling is delivered via phone or Zoom.
Weekly counseling sessions for 8 weeks
Duration - Up to 6 months after baseline
Participants complete assessments and saliva tests to evaluate smoking cessation and lung cancer screening completion.
Assessments at 1, 3, and 6 months; saliva tests at 3 and 6 months
Trial Site Locations
Total: 2 locations
1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115
Actively Recruiting
2
University of Massachusetts-Boston
Boston, Massachusetts, United States, 02125
Actively Recruiting
Research Team
M
Mary Cooley, PhD
B
Barbara Halpenny, MA, MSW
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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