Randomized Clinical Trial of A Culturally Aligned Digital Smoking Cessation Resource for American Indian Persons

What this Trial Is About

Researchers are evaluating a culturally aligned digital smoking cessation program designed specifically for American Indian and Alaska Native persons who smoke. This randomized controlled trial compares this culturally tailored resource to a general, standard smoking cessation text messaging program. The study aims to examine the effectiveness of these programs in helping participants quit smoking combustible tobacco products. Participants will be randomly assigned to one of two groups: one receiving the culturally aligned smoking cessation text message program and the other receiving the standard text message program. Both groups will use their assigned program for six months. The study includes surveys at the start and at 1, 3, and 6 months to gather information about program use and smoking behavior. Additionally, carbon monoxide levels in exhaled breath will be measured at 1, 3, and 6 months using a specialized device to biochemically confirm smoking abstinence. During the study, participants will complete questionnaires about their smoking habits and program usage. Researchers will track smoking abstinence rates confirmed by breath tests after six months as the main outcome. Secondary measures include abstinence rates at earlier time points, self-reported quit attempts, cigarette use, and use of nicotine replacement or other support methods. Participation lasts for six months, with ongoing monitoring through surveys and breath tests to assess quitting success and program engagement.

American Indian Smokefree Native RCT