Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07509606

Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)

Led by National Cheng Kung University · Updated on 2026-04-03

102

Participants Needed

1

Research Sites

142 weeks

Total Duration

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AI-Summary

What this Trial Is About

Chronic obstructive pulmonary disease (COPD) is an irreversible disorder characterized by persistent airflow limitation and increased lung compliance. It leads to dyspnea, skeletal muscle dysfunction, impaired functional capacity, and reduced quality of life. Physical inactivity is considered a major contributor to symptom deterioration, the development of a vicious cycle, and ultimately increased mortality. According to the American College of Sports Medicine (ACSM), the American Thoracic Society (ATS), and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), pulmonary rehabilitation should include aerobic and resistance exercise for at least 20 minutes per session, performed three to five times per week for a minimum of 12 weeks. Exercise intensity should be progressively increased to exceed 60% of peak oxygen uptake (VO₂peak), and patients are encouraged to maintain long-term exercise habits. However, there is still no consensus regarding the optimal initial intensity, progression strategy, and exercise duration. Previous studies have demonstrated that whole-body vibration (WBV) can improve lower extremity muscle strength, functional capacity, and quality of life in patients with COPD. However, its effects on lung function and the optimal training dose remain unclear. In addition, COPD also affects respiratory muscles, upper extremity strength and flexibility, as well as cardiac autonomic function. Therefore, the aim of this study is to investigate the effects of different WBV frequencies on lung function, respiratory muscle function, upper extremity strength and flexibility, and cardiac autonomic function, in order to determine the optimal training dose.

CONDITIONS

Official Title

Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy individuals with no prior whole-body vibration therapy or exposure to vibration-related jobs or sports
  • Aged between 18 and 65 years
  • Clinically diagnosed with COPD at GOLD stage II, III, or IV
  • No hospitalization in the past two months
  • No rehabilitation program participation in the past two months
  • Able to follow the exercise training program
  • Aged 18 years or older
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Acute thrombosis
  • Severe cardiovascular disease
  • Presence of a cardiac pacemaker
  • Recent wounds from injury or surgery
  • Hip or knee implants
  • Acute hernia, disc degeneration, or spondylolysis
  • Severe diabetes mellitus
  • Epilepsy
  • Recent infection
  • Severe migraine
  • Tumor
  • Recently implanted intrauterine device, metal pins, or plates
  • Kidney stones
  • Organ failure
  • Musculoskeletal, respiratory, neurological, cardiovascular conditions or any acute or chronic pain
  • Participation in other research studies at the same time
  • Regular moderate-intensity exercise 3 or more times per week
  • Severe respiratory diseases like bronchiectasis, pulmonary fibrosis, asthma, or tuberculosis
  • Current smokers
  • Severe joint disease or history of lower extremity surgery
  • History of vitreous hemorrhage
  • Dependence on supplemental oxygen
  • Severe alcohol abuse (over 80 g/day)
  • Severe malnutrition (BMI less than 19 kg/m)
  • Altered consciousness or inability to comply with assessments

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Cheng Kung University Hospital

Tainan, Taiwan, 701

Actively Recruiting

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Research Team

K

Kun-Ling Tasi, PhD

CONTACT

T

Ting-Ying Wu, B.S

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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