Actively Recruiting
Adaptive Optics Imaging of Outer Retinal Diseases
Led by Food and Drug Administration (FDA) · Updated on 2026-05-08
100
Participants Needed
2
Research Sites
370 weeks
Total Duration
On this page
Sponsors
F
Food and Drug Administration (FDA)
Lead Sponsor
N
National Eye Institute (NEI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement membrane or choroidal pathologies) to develop new diagnostic methods, biomarkers, and clinical endpoints.
CONDITIONS
Official Title
Adaptive Optics Imaging of Outer Retinal Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Are 21 years of age or older
- Can follow instructions during adaptive optics imaging similar to a clinical eye exam
- Can understand and sign informed consent (non-English speakers excluded)
- Have been diagnosed with an outer retinal disease or condition (for affected group)
You will not qualify if you...
- Have a condition preventing adequate imaging such as unstable fixation or eye media opacity
- Have vision correction outside the range of +4 to -8 diopters
- Have a history of allergic reaction to mydriatic eye drops
- Have narrow iridocorneal angle or a history of acute angle closure glaucoma
- Are working directly under supervision of specified doctors or NIH/NEI principal investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
NIH Clinical Center
Bethesda, Maryland, United States, 20810
Actively Recruiting
2
Food and Drug Administration
Silver Spring, Maryland, United States, 20993
Actively Recruiting
Research Team
D
Daniel X Hammer, Ph.D.
CONTACT
Z
Zhuolin Liu, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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