Actively Recruiting

Age: 50Years +
All Genders
Healthy Volunteers
ID06924021

Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

Led by University of Wisconsin, Madison · Updated on 2026-03-27

1000

Participants Needed

14

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers aim to create a diverse and detailed dataset of eye images from 1000 participants aged 50 and older, including both healthy individuals and those diagnosed with any stage of Age-Related Macular Degeneration (AMD). This dataset will support the development of an Artificial Intelligence (AI) tool to help screen for early AMD, a condition that can lead to vision loss. The study addresses the challenge of identifying early AMD in primary care settings to help prevent late-stage vision loss. Participants will undergo a single retinal imaging session of both eyes, which includes single field stereo color fundus photography before and after pupil dilation and macular spectral domain-optical coherence tomography. Additional study procedures include collecting patient history such as demographics, smoking, and family history of AMD, a physical exam measuring height and weight, vision testing using Snellen best-corrected visual acuity, and AMD classification using the Beckman scale. The study is observational and cross-sectional, conducted at multiple international sites to ensure a wide representation. During the study, participants will provide detailed imaging and clinical data in one visit. Researchers will collect and annotate images for a reference standard classification of AMD and track participant counts by AMD classification and geographic location over up to 18 months. The study involves no treatment but focuses on data collection to facilitate AI development. Participation involves no therapeutic procedures, and safety monitoring is not required since this is an observational study. Total involvement is limited to the imaging session and consent process.

CONDITIONS

Brief Title

Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

Who Can Participate

Age: 50Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged 50 years or older at the time of signing the informed consent form
  • Willing to comply with all study procedures and sign the informed consent form
  • Individuals with normal healthy eyes or diagnosed with any stage of Age-Related Macular Degeneration, confirmed by Central Reading Center
Not Eligible

You will not qualify if you...

  • Receiving therapeutic treatment for any type of Age-Related Macular Degeneration in either eye (AREDS2 supplements allowed)
  • Unable to obtain adequate quality retinal images as determined by Central Reading Center
  • Severe vision loss requiring urgent surgery
  • Contraindications for retinal imaging such as narrow anterior chamber angles or hypersensitivity to light
  • Presence of systemic or ocular conditions that would prevent participation in the study
  • Unwilling to sign informed consent
  • Currently or previously enrolled in an interventional AMD clinical trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo a one-time retinal imaging session and related assessments to collect detailed eye health data and classify age-related macular degeneration status.

1 visit (in-person)

Trial Site Locations

Total: 14 locations

1

Bergstrom Eye Research LLC

Fargo, North Dakota, United States, 58103

Actively Recruiting

2

Erie Retina Research

Erie, Pennsylvania, United States, 16507

Actively Recruiting

3

Retina Foundation of the Southwest

Dallas, Texas, United States, 75231

Actively Recruiting

4

Valley Retina Institute

McAllen, Texas, United States, 78503

Actively Recruiting

5

Retina Consultants of Texas (Houston)

The Woodlands, Texas, United States, 77384

Actively Recruiting

6

University of Utah - John A. Moran Eye Center

Salt Lake City, Utah, United States, 84132

Actively Recruiting

7

University Station Eye Care Clinic

Madison, Wisconsin, United States, 53705

Actively Recruiting

8

Charles Research Center

Buenos Aires, Argentina

Not Yet Recruiting

9

Adelaide Eye and Retina Centre

Adelaide, Australia, 5000

Not Yet Recruiting

10

Centre Hospialier Intercommunal de Paradis (Centre Monticelli Paradis)

Marseille, France, 13008

Not Yet Recruiting

11

University of Bonn - Department of Ophthalmology

Bonn, Germany, 53127

Not Yet Recruiting

12

Sankara Nethralaya, Medical Research Foundation

Chennai, Tamil Nadu, India, 600006

Actively Recruiting

13

Aravind Eye Hospital

Chennai, Tamil Nadu, India, 641014

Actively Recruiting

14

Aga Khan University

Karachi, Pakistan, 74800

Actively Recruiting

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Research Team

W

Wisconsin Reading Center

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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