Actively Recruiting
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
Led by University of Wisconsin, Madison · Updated on 2026-03-27
1000
Participants Needed
14
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers aim to create a diverse and detailed dataset of eye images from 1000 participants aged 50 and older, including both healthy individuals and those diagnosed with any stage of Age-Related Macular Degeneration (AMD). This dataset will support the development of an Artificial Intelligence (AI) tool to help screen for early AMD, a condition that can lead to vision loss. The study addresses the challenge of identifying early AMD in primary care settings to help prevent late-stage vision loss. Participants will undergo a single retinal imaging session of both eyes, which includes single field stereo color fundus photography before and after pupil dilation and macular spectral domain-optical coherence tomography. Additional study procedures include collecting patient history such as demographics, smoking, and family history of AMD, a physical exam measuring height and weight, vision testing using Snellen best-corrected visual acuity, and AMD classification using the Beckman scale. The study is observational and cross-sectional, conducted at multiple international sites to ensure a wide representation. During the study, participants will provide detailed imaging and clinical data in one visit. Researchers will collect and annotate images for a reference standard classification of AMD and track participant counts by AMD classification and geographic location over up to 18 months. The study involves no treatment but focuses on data collection to facilitate AI development. Participation involves no therapeutic procedures, and safety monitoring is not required since this is an observational study. Total involvement is limited to the imaging session and consent process.
CONDITIONS
Brief Title
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 50 years or older at the time of signing the informed consent form
- Willing to comply with all study procedures and sign the informed consent form
- Individuals with normal healthy eyes or diagnosed with any stage of Age-Related Macular Degeneration, confirmed by Central Reading Center
You will not qualify if you...
- Receiving therapeutic treatment for any type of Age-Related Macular Degeneration in either eye (AREDS2 supplements allowed)
- Unable to obtain adequate quality retinal images as determined by Central Reading Center
- Severe vision loss requiring urgent surgery
- Contraindications for retinal imaging such as narrow anterior chamber angles or hypersensitivity to light
- Presence of systemic or ocular conditions that would prevent participation in the study
- Unwilling to sign informed consent
- Currently or previously enrolled in an interventional AMD clinical trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a one-time retinal imaging session and related assessments to collect detailed eye health data and classify age-related macular degeneration status.
1 visit (in-person)
Trial Site Locations
Total: 14 locations
1
Bergstrom Eye Research LLC
Fargo, North Dakota, United States, 58103
Actively Recruiting
2
Erie Retina Research
Erie, Pennsylvania, United States, 16507
Actively Recruiting
3
Retina Foundation of the Southwest
Dallas, Texas, United States, 75231
Actively Recruiting
4
Valley Retina Institute
McAllen, Texas, United States, 78503
Actively Recruiting
5
Retina Consultants of Texas (Houston)
The Woodlands, Texas, United States, 77384
Actively Recruiting
6
University of Utah - John A. Moran Eye Center
Salt Lake City, Utah, United States, 84132
Actively Recruiting
7
University Station Eye Care Clinic
Madison, Wisconsin, United States, 53705
Actively Recruiting
8
Charles Research Center
Buenos Aires, Argentina
Not Yet Recruiting
9
Adelaide Eye and Retina Centre
Adelaide, Australia, 5000
Not Yet Recruiting
10
Centre Hospialier Intercommunal de Paradis (Centre Monticelli Paradis)
Marseille, France, 13008
Not Yet Recruiting
11
University of Bonn - Department of Ophthalmology
Bonn, Germany, 53127
Not Yet Recruiting
12
Sankara Nethralaya, Medical Research Foundation
Chennai, Tamil Nadu, India, 600006
Actively Recruiting
13
Aravind Eye Hospital
Chennai, Tamil Nadu, India, 641014
Actively Recruiting
14
Aga Khan University
Karachi, Pakistan, 74800
Actively Recruiting
Research Team
W
Wisconsin Reading Center
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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