Actively Recruiting
Adipose Tissue Inflammation and Diabetes Development Study (Fettvävsinflammation Och Diabetesutveckling)
Led by Göteborg University · Updated on 2025-05-06
18
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research focuses on obese individuals undergoing abdominoplasty surgery to study how adding resolution molecules might reduce inflammation and insulin resistance in their fat tissue. The study aims to see if these laboratory results match the patients' own resolution profiles related to inflammation and diabetes development. Participants are classified based on their metabolic health status after surgery. The study involves collecting tissue samples during the abdominoplasty procedure to analyze inflammatory markers and insulin resistance. No specific treatments or drugs are given as this is an observational study. Participants will be involved in assessments mainly around the time of their surgery, with researchers measuring inflammatory status as the primary outcome by 2025. The study tracks inflammatory markers in tissue to understand diabetes development better. Participation involves observation and tissue analysis without altering standard care.
CONDITIONS
Brief Title
Adipose Inflammation and Diabetes (FAB)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Body mass index (BMI) between 30 and 40 kg/m2
- Excess skin (ptosis) greater than 3 cm
- Gastric bypass surgery performed more than 2 years ago
- Stable weight for at least 6 months before surgery
- Non-smoker for at least 6 weeks prior to surgery
You will not qualify if you...
- Unable to understand spoken and written Swedish
- American Society of Anesthesiologists (ASA) classification of 3 or higher
- Neurological, orthopedic, or rheumatologic injury or illness affecting physical ability
- Known hernia requiring surgery before operation
- Severe mental illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo abdominoplasty surgery to collect adipose tissue for study.
1 surgery visit (in-person)
Duration - Up to 6 months
Participants are monitored after surgery to assess recovery and inflammatory status.
Approximately 3 follow-up visits
Trial Site Locations
Total: 1 location
1
Sahlgrenska university hospital
Gothenburg, Västra Götaland County, Sweden, 40530
Actively Recruiting
Research Team
E
Emma Borgeson, PhD
C
Christina Biörserud, RN, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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