Actively Recruiting

Phase Not Applicable
Age: 60Years - 70Years
FEMALE
ID07627919

Effect of Combined Resistance Training and High-Protein Diet on Frailty in Sarcopenic Elderly Women

Led by Cairo University · Updated on 2026-06-04

60

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effects of combining resistance exercise training and a high-protein diet on frailty in elderly obese women diagnosed with sarcopenia. The study will recruit sixty women aged 60 to 70 years who meet specific sarcopenia criteria, focusing on improving muscle strength and overall health. Participants will be randomly assigned to different groups to assess the combined impact of exercise and nutrition on their condition. Participants in Group A will engage in supervised resistance exercise sessions three times weekly for 12 weeks, starting with warming up, followed by various strength exercises like leg press and chest press with gradual increases in intensity and duration. They will also follow a high-protein diet providing 1.3 grams of protein per kilogram of body weight daily, spread evenly across meals, with dietary intake monitored biweekly. Group B will receive the same high-protein diet and general health advice but will maintain their usual lifestyle without structured exercise during the study period; they will be offered the exercise program after the trial. Throughout the 12 weeks, participants will be monitored through assessments including balance testing, handgrip strength, muscle quality, body measurements like waist-to-hip ratio and body mass index, and quality of life evaluations. Exercise attendance and dietary adherence will be tracked through training logs and dietary records. The study's primary goal is to observe balance improvements, with other health and muscle-related measures as secondary outcomes, to understand how combined exercise and diet interventions affect frailty in this population.

CONDITIONS

Brief Title

Effect of Combined Resisted Training and Protein-based Diet on Frailty in Sarcopenic Elderly Women

Who Can Participate

Age: 60Years - 70Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female gender
  • Age between 60 and 70 years
  • Body mass index (BMI) of 30 kg/m2 or higher
  • Diagnosed with sarcopenia by a physician using EWGSOP2 criteria, including low muscle strength and low muscle quantity confirmed by tests
  • SARC-F score greater than 3
  • Able to walk and participate in exercise
  • Stable medical condition
  • No diet followed in the 4 weeks before treatment
  • No exercise program followed in the 4 weeks before treatment
Not Eligible

You will not qualify if you...

  • Severe cardiovascular, pulmonary, renal, or liver disease
  • Uncontrolled diabetes or high blood pressure
  • Neurological or musculoskeletal disorders preventing exercise
  • Cancer or other terminal illness
  • Current use of anti-inflammatory drugs or steroids
  • Metal implants preventing body composition assessment
  • Cognitive impairment affecting consent or following instructions
  • Use of drugs affecting metabolism or balance
  • Use of walking assistive devices

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 12 weeks

Participants in Group A perform supervised resistance exercise training three times per week and follow a high-protein diet. Participants in Group B follow a high-protein diet and receive general health advice without structured exercise.

Exercise sessions 3 times per week for Group A; dietary records collected every two weeks for Group A; check-in contacts every two weeks for Group B

Trial Site Locations

Total: 1 location

1

Fawkia hospital outpatient clinic

El-Sheikh Zayed City, Egypt

Actively Recruiting

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Research Team

S

Shaimaa Elsayed, master

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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