Actively Recruiting
Adult SMA Research and Clinical Hub
Led by Newcastle-upon-Tyne Hospitals NHS Trust · Updated on 2025-05-18
600
Participants Needed
18
Research Sites
248 weeks
Total Duration
On this page
Sponsors
N
Newcastle-upon-Tyne Hospitals NHS Trust
Lead Sponsor
N
Newcastle University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Adult SMA REACH is a data collection study aiming to gain a better understanding of the impact of standards of care and new treatments on the natural history of Spinal Muscular Atrophy (SMA). This study is sponsored by The Newcastle upon Tyne Hospitals NHS Foundation Trust. Adult SMA REACH is funded by Biogen and Roche. Currently, there are three drug treatments available for SMA in the UK: Zolgensma, Nusinersen and Risdiplam. Zolgensma is the only approved drug - Nusinersen and Risdiplam are currently available as part of Managed Access Agreements (MAA).
CONDITIONS
Official Title
Adult SMA Research and Clinical Hub
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 61 16 years
- Genetically confirmed diagnosis of 5q SMA
- Signed informed consent to take part in the study
You will not qualify if you...
- Non-5q SMA
- No genetic confirmation
- Under 16 years of age
- No signed informed consent or consent withdrawn
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
University Hospitals Birmingham NHS Foundation Trust
Birmingham, United Kingdom, B15 2GW
Actively Recruiting
2
North Bristol NHS Trust
Bristol, United Kingdom, BS10 5NB
Actively Recruiting
3
Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom, CB2 0QQ
Actively Recruiting
4
Cardiff and Vale University Health Board
Cardiff, United Kingdom, CF14 4XW
Actively Recruiting
5
NHS Greater Glasgow and Clyde
Glasgow, United Kingdom, G12 0XH
Actively Recruiting
6
Bradford Teaching Hospitals NHS Foundation Trust
Leeds, United Kingdom, BD9 6RJ
Actively Recruiting
7
The Walton Centre NHS Foundation Trust
Liverpool, United Kingdom, L9 7LJ
Actively Recruiting
8
University College London Hospitals NHS Foundation Trust
London, United Kingdom, NW1 2BU
Actively Recruiting
9
King's College Hospital NHS Foundation Trust
London, United Kingdom, SE5 9RS
Actively Recruiting
10
St George's University NHS Foundation Trust
London, United Kingdom, SW17 0QT
Actively Recruiting
11
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle upon Tyne, United Kingdom, NE1 3BZ
Actively Recruiting
12
Nottingham University Hospitals Trust
Nottingham, United Kingdom, NG5 1PB
Actively Recruiting
13
The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust
Oswestry, United Kingdom, SY10 7AG
Actively Recruiting
14
Oxford University Hospitals Trust
Oxford, United Kingdom, OX3 9DU
Actively Recruiting
15
The Northern Care Alliance NHS Foundation Trust
Salford, United Kingdom, M6 8HD
Actively Recruiting
16
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, United Kingdom, S10 2JF
Actively Recruiting
17
University Hospital Southampton NHS Foundation Trust
Southampton, United Kingdom, SO16 6YD
Actively Recruiting
18
South West Wales Neuromuscular Service in Swansea
Swansea, United Kingdom, SA6 6NL
Actively Recruiting
Research Team
A
Adult SMA REACH Team
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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