Actively Recruiting

Age: 20Years - 100Years
All Genders
Healthy Volunteers
ID05794061

Advances in Neuropsychological Diagnostics for Cognitive and Psychiatric Disorders

Led by Istituto Auxologico Italiano ยท Updated on 2025-09-17

300

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to improve neuropsychological diagnostics by developing, calibrating, and evaluating new clinical and forensic neuropsychological tests. These tests focus on both instrumental and non-instrumental functions and are being studied in neurologically healthy individuals representing the Italian population, as well as in patients with various neurological and neuropsychiatric conditions. The goal is to modernize and expand diagnostic tools to meet clinical and forensic needs, including remote testing and assessments of testamentary capacity. Participants include people with brain disorders and neurologically healthy controls. The study involves cognitive and behavioral tests and questionnaires designed to assess various mental functions. These tests will be administered at baseline, then repeated after one month for healthy participants, and at 6, 12, and 18 months for those with neurodegenerative disorders to evaluate changes over time. Throughout the study, participants will undergo multiple assessments including tests like the Brief Assessment of Social Skills-Dementia, Picture Interpretation Test, and Telephone Interview for Cognitive Status among others. These evaluations are done at enrollment and at scheduled intervals to monitor cognitive and behavioral changes. The study will track outcomes to understand test reliability and clinical usefulness over an extended period, with participation lasting up to 18 months for some individuals.

CONDITIONS

Brief Title

Advances in Neuropsychological Diagnostics

Who Can Participate

Age: 20Years - 100Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 20 to 100 years
  • Clinical diagnosis of neurological or psychiatric disorders for clinical populations
  • Neurologically healthy individuals for healthy controls
Not Eligible

You will not qualify if you...

  • Clinical diagnosis not of interest for clinical populations
  • Severe general medical conditions
  • Uncorrected vision or hearing deficits
  • Presence of brain disorders for healthy controls

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Baseline, 1 month, and up to 18 months

Participants complete neuropsychological instruments including cognitive and behavioral tests and questionnaires at enrollment and subsequent time points.

Multiple visits at baseline, 1 month, 6 months, 12 months, and 18 months

Long-term Monitoring

Duration - Up to 18 months

Participants with neurodegenerative disorders are monitored over time to assess changes in cognitive and psychiatric function.

Follow-up visits at 6, 12, and 18 months

Trial Site Locations

Total: 1 location

1

Istituto Auxologico Italiano IRCCS

Milan, Lombardy, Italy, 20122

Actively Recruiting

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Research Team

N

Nadia Bolognini, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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