Actively Recruiting

Age: 25Years - 35Years
All Genders
Healthy Volunteers
NCT04543461

American Lung Association (ALA) Lung Health Cohort

Led by Johns Hopkins University · Updated on 2026-02-04

4000

Participants Needed

37

Research Sites

252 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.

CONDITIONS

Official Title

American Lung Association (ALA) Lung Health Cohort

Who Can Participate

Age: 25Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 25-35 years at the time of the baseline examination
  • Able to read and understand English or Spanish
  • Has a social security number
  • Resident (citizen or non-citizen) of the United States for at least 12 months prior to examination
  • Willing to provide contact information for at least 2 proxies who know your whereabouts and vital status
Not Eligible

You will not qualify if you...

  • Severe asthma requiring high-level therapy or frequent healthcare visits/hospitalization in the past 12 months
  • History of chronic lung diseases other than asthma, including COPD, cystic fibrosis, pulmonary fibrosis, pulmonary hypertension
  • Current pregnancy
  • History of cancer other than non-melanoma skin cancer
  • Diagnosed cardiovascular diseases such as congenital or coronary heart disease
  • Inability or unwillingness to provide informed consent or perform study procedures
  • Unable to be contacted by phone or email
  • Any condition putting participant at risk as judged by a physician
  • Being institutionalized

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 37 locations

1

University Of Alabama

Birmingham, Alabama, United States, 35294

Actively Recruiting

2

University of Arizona-Tuscon

Tucson, Arizona, United States, 85724

Actively Recruiting

3

University of California, Los Angeles

Los Angeles, California, United States, 90095

Actively Recruiting

4

University of California, San Francisco

San Francisco, California, United States, 94143

Actively Recruiting

5

University of Colorado

Aurora, Colorado, United States, 80045

Active, Not Recruiting

6

National Jewish Health

Denver, Colorado, United States, 80206

Actively Recruiting

7

Nemours Children's Jacksonville

Jacksonville, Florida, United States, 32207

Actively Recruiting

8

University of Florida, Jacksonville

Jacksonville, Florida, United States, 32209

Actively Recruiting

9

University of Illinois at Chicago

Chicago, Illinois, United States, 60608

Actively Recruiting

10

Northwestern University

Chicago, Illinois, United States, 60611

Actively Recruiting

11

Rush Universtiy

Chicago, Illinois, United States, 60612

Actively Recruiting

12

University of Chicago

Chicago, Illinois, United States, 60637

Withdrawn

13

St. Vincent's Health System

Indianapolis, Indiana, United States, 46260

Withdrawn

14

University of Iowa

Iowa City, Iowa, United States, 52242

Actively Recruiting

15

University of Kansas

Kansas City, Kansas, United States, 66103

Actively Recruiting

16

Johns Hopkins University

Baltimore, Maryland, United States, 21218

Actively Recruiting

17

Brigham and Women's

Boston, Massachusetts, United States, 02115

Withdrawn

18

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

19

Presbyterian Brooklyn Methodist Hospital

Brooklyn, New York, United States, 11215

Not Yet Recruiting

20

New York Medical College

Hawthorne, New York, United States, 10532

Actively Recruiting

21

New York University

New York, New York, United States, 10016

Withdrawn

22

Mt. Sinai, NYC

New York, New York, United States, 10029

Actively Recruiting

23

Columbia University

New York, New York, United States, 10032

Not Yet Recruiting

24

Cornell University

New York, New York, United States, 10032

Actively Recruiting

25

University of Rochester

Rochester, New York, United States, 14642

Actively Recruiting

26

University of North Carolina Hospital

Chapel Hill, North Carolina, United States, 27517

Active, Not Recruiting

27

Duke University

Durham, North Carolina, United States, 27710

Actively Recruiting

28

Wake Forest School of Medicine

Winston-Salem, North Carolina, United States, 27104

Actively Recruiting

29

Ohio State University

Columbus, Ohio, United States, 43210

Actively Recruiting

30

Temple University

Philadelphia, Pennsylvania, United States, 19140

Actively Recruiting

31

University of Pittsburg-Emphysema/COPD Research Center

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

32

Medical University of South Carolina

Charleston, South Carolina, United States, 29425

Actively Recruiting

33

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37235

Actively Recruiting

34

Baylor College of Medicine

Houston, Texas, United States, 77030

Actively Recruiting

35

University of Vermont

Colchester, Vermont, United States, 05446

Actively Recruiting

36

University of Washington

Seattle, Washington, United States, 98108

Not Yet Recruiting

37

University of Wisconsin Madison

Madison, Wisconsin, United States, 53792

Withdrawn

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Research Team

E

Elizabeth Sugar, PhD

CONTACT

C

Curt Reynolds, MAS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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