Actively Recruiting
Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA
Led by Istituto Ortopedico Rizzoli · Updated on 2026-02-27
50
Participants Needed
1
Research Sites
97 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is: ● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population? Participants will undergo: * Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment
CONDITIONS
Official Title
Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 65 and 80 years
- Kellgren score II or III
- No history of falls in the last 12 months
You will not qualify if you...
- Any musculoskeletal, neurological, rheumatic, or tumoral diseases
- Dementia
- Diabetes
- Inguinal or abdominal hernia
- Severe Hypertension (Level 3)
- Severe Cardio-pulmonary insufficiency
- Diagnosis of Osteonecrosis in the lower limb joints
- Conditions incompatible with MRI or electrostimulation (e.g., implanted biomedical devices, epilepsy, severe venous insufficiency in lower limbs)
- Previous interventions or trauma to the joints of the lower limb
AI-Screening
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Trial Site Locations
Total: 1 location
1
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy, 40136
Actively Recruiting
Research Team
L
Lisa Berti, Professor
CONTACT
M
Massimiliano Baleani, Engineer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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