Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
ID07590700

Effectiveness of Fall-Preventive Home Exercise Programs in Patients With Parkinson Disease: A Randomized Controlled Trial

Led by Uludag University · Updated on 2026-05-19

30

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Falls are common among patients with Parkinson disease and can lead to reduced mobility, fear of falling, loss of independence, and injury. Researchers are comparing two home-based exercise programs to see which one better reduces fall risk and improves functional outcomes in this population. This randomized controlled trial focuses on patients with Parkinson disease at Hoehn and Yahr stage 3 or 4 who have had the diagnosis for at least 5 years. Participants will be randomly assigned to one of two exercise groups. One group will follow the Otago Home Exercise Program, which includes strengthening, static balance, and dynamic balance exercises to improve lower body strength and balance. The other group will participate in a structured home exercise program focusing on spinal stabilization and strengthening of specific muscle groups. Both programs last 6 weeks, with exercises performed three times a week for about 40 minutes per session. At week 3, exercises will be reviewed and adjusted based on each participant's functional status. Participants will be assessed at the start, at week 3, and at week 6. Evaluations include measures related to fall risk, freezing of gait, functional mobility, gait speed, postural control, and physical performance tests like the Timed Up and Go and Sit-to-Stand tests. Researchers will monitor progress and outcomes using questionnaires and physical tests to understand which program more effectively supports fall prevention and mobility in Parkinson disease patients.

CONDITIONS

Brief Title

Home-Based Exercise Programs for Fall Prevention in Parkinson Disease

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Parkinson disease confirmed by a neurologist
  • Hoehn and Yahr stage 3 or 4 Parkinson disease
  • Diagnosis of Parkinson disease for at least 5 years
  • Willingness to participate in the study and provide written informed consent
  • Ability to walk independently or with minimal assistance
  • Mini-Mental State Examination score >24
Not Eligible

You will not qualify if you...

  • Balance or gait impairment due to causes other than Parkinson disease, such as severe orthopedic problems or another neurological disease
  • Red flags suggestive of Parkinson-plus syndromes, such as symmetric onset, early falls, early-onset dementia, or gaze palsy
  • History of serious fall-related injury or surgery within the last 6 months
  • Any additional health condition that would prevent participation in the exercise program during the study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 6 weeks

Participants perform a home-based exercise program 3 times per week for 6 weeks. The program includes either the Otago Home Exercise Program or a structured home exercise program, both designed to improve muscle strength, balance, and mobility. The exercise program will be reviewed and progressed at week 3 according to the participant's functional status.

Baseline visit and visit at week 3 for program review

Trial Site Locations

Total: 1 location

1

Hatay Mustafa Kemal University

Hatay, Antakya, Turkey (Türkiye)

Actively Recruiting

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Research Team

S

Selim GÜNAY, Asst Prof

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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