Actively Recruiting

Age: 8Years +
All Genders
Healthy Volunteers
NCT05197946

Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

Led by Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · Updated on 2025-05-02

300

Participants Needed

4

Research Sites

383 weeks

Total Duration

On this page

Sponsors

H

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Lead Sponsor

J

Johns Hopkins University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.

CONDITIONS

Official Title

Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

Who Can Participate

Age: 8Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Individual 8 years of age or older
  • Diagnosis of cerebral palsy (for CP participants)
  • Adult participants able to give informed consent OR participants who assent with legal representative consent
  • Clinical imaging showing isolated periventricular white matter injury (for CP participants undergoing MRI)
  • Clinical judgment that neurologic symptoms are due to stable periventricular white matter injury (for CP MRI participants)
  • Ability to lie still in MRI scanner for up to 1.5 hours (for participants undergoing MRI)
  • Neurotypical participants must be 8 years or older and able to consent (for survey and MRI groups)
Not Eligible

You will not qualify if you...

  • Neurotypical participants with clinically significant neurological or developmental diagnoses

AI-Screening

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Trial Site Locations

Total: 4 locations

1

F.M. Kirby Center

Baltimore, Maryland, United States, 21205

Actively Recruiting

2

Mt. Washington Pediatric Hospital

Baltimore, Maryland, United States, 21209

Actively Recruiting

3

Johns Hopkins Hospital

Baltimore, Maryland, United States, 21287

Actively Recruiting

4

Kennedy Krieger Institute

Baltimore, Maryland, United States, 21287

Actively Recruiting

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Research Team

P

Paul Salib, MS

CONTACT

E

Eric Chin, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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