Imaging Brain and Spinal Changes Linked to Chronic Pain in People With Cerebral Palsy Age 8 and Older

What this Trial Is About

Researchers are studying chronic pain and sensory problems in people with cerebral palsy CP, focusing on how brain networks related to movement and sensation may be affected. This study aims to better understand different types of pain in CP by using MRI scans and reviewing medical records along with patient reports to find brain changes linked to pain and sensory loss. Participants will complete online questionnaires about their pain, medical history, and demographics. For those who consent, medical records and past clinical MRI scans will be reviewed for brain injury markers related to CP and pain. Some participants will undergo research MRI scans that last up to 1.5 hours, including brain and spinal imaging without contrast agents. These scans are scheduled close to when surveys are completed, with follow-up surveys if scans occur later. During the study, participants will provide survey responses and may have MRI scans. Researchers will review brain and spinal volumes and diffusion measures within three months of surveys. The study collects data from medical records, questionnaires, and imaging to identify neurobiomarkers linked to pain and sensory deficits in CP. Participation involves completing surveys and possibly attending MRI sessions, with the study running until December 2028.

Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy