Actively Recruiting

Age: 18Years - 42Years
FEMALE
NCT06124261

Androgens and NAFLD Longitudinal Cohort Study

Led by University of California, San Francisco · Updated on 2026-04-13

150

Participants Needed

2

Research Sites

253 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

D

Duke University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time. NAFLD happens when fat builds up in the liver which can cause damage to the liver such as inflammation or scarring. Young women with a condition called polycystic ovary syndrome (PCOS) have a high risk for NAFLD, and they often have high androgen levels too. So the researchers are recruiting young women with PCOS as well as those without PCOS, and will compare changes in NAFLD over time between young women with and without PCOS. This study is funded by the National Institutes of Health

CONDITIONS

Official Title

Androgens and NAFLD Longitudinal Cohort Study

Who Can Participate

Age: 18Years - 42Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with metabolic associated steatohepatitis (MASH)
  • Diagnosed with polycystic ovary syndrome (PCOS) or without PCOS
Not Eligible

You will not qualify if you...

  • Consuming more than 7 alcoholic drinks per week
  • Currently pregnant
  • Having other causes of hepatic steatosis
  • Weight loss of more than 10% body weight in the last 6 months

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

University of California San Francisco

San Francisco, California, United States, 94143

Actively Recruiting

2

Duke University

Durham, North Carolina, United States, 27708

Not Yet Recruiting

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Research Team

L

Lily C Carbullido, B.S.

CONTACT

J

Jasmine Gamez

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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