Actively Recruiting

Age: 20Years - 80Years
All Genders
ID05762991

Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion: A Multihospital Study

Led by National Taiwan University Hospital · Updated on 2025-06-22

2000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how artificial intelligence (AI) can help diagnose Helicobacter pylori infection and premalignant gastric lesions by analyzing upper endoscopic images. The study focuses on linking these images with urea breath test results and histopathological findings to improve diagnosis accuracy. The goal is to support clinicians, especially in rural areas, through a telemedicine system that assists in detecting these conditions and potentially links to gastric cancer risk. Participants undergo urea breath tests, upper gastrointestinal endoscopy, and histology examinations. The AI analyzes the correlation between the collected endoscopic images and the test results. This approach will be developed into a telemedicine service to assist healthcare providers in remote locations, such as the Matsu Islands. Throughout the study, researchers collect and review test results, endoscopic images, and histopathological data. They will measure how sensitive the AI is in detecting premalignant gastric lesions over up to five years and assess its ability to accurately exclude these conditions. The study runs until the end of 2026, allowing long-term follow-up and evaluation of the AI system's diagnostic performance.

CONDITIONS

Brief Title

Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion

Who Can Participate

Age: 20Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 20 and 80 years
  • Scheduled to undergo urea breath test and upper gastrointestinal endoscopy
Not Eligible

You will not qualify if you...

  • History of gastric surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Up to 1 day

Participants undergo urea breath test, upper gastrointestinal endoscopy, and histology examination to collect diagnostic data.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 5 years

Participants' diagnostic results and endoscopic images are monitored to analyze the correlation and assist in diagnosing Helicobacter pylori infection and detecting premalignant gastric lesions.

Trial Site Locations

Total: 1 location

1

Yi-Chia Lee

Taipei, Taiwan, 10015

Actively Recruiting

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Research Team

Y

Yi-Chia Lee, MD, PhD

T

Tsung-Hsien Chiang, MD,PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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