Actively Recruiting
Application of Biomarkers in Neurological Diseases
Led by Yi Yang · Updated on 2024-03-01
3000
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to explore the predictive and diagnostic roles of biomarkers in patients with neurological diseases. It focuses on using proteomics and metabolomics technologies to study brain tissue, plasma, and cerebrospinal fluid to identify potential new biomarkers. The study seeks to better understand biomarker expression in healthy individuals compared to those with neurological conditions and to address unresolved challenges in this early-stage research. Patients admitted to hospital or emergency departments with neurological diseases will be observed. Clinical data, laboratory data, imaging data, and blood and tissue samples will be collected at baseline and during follow-up at various time points in acute and chronic phases. This observational approach does not involve experimental treatments but gathers comprehensive information to support biomarker research. Participants will be monitored through clinical evaluations including a modified Rankin Scale score at 90 days. The study involves consented collection of samples without affecting patient diagnosis or treatment. Data will help researchers assess biomarker characteristics and their relation to disease progression and outcomes. The study is planned to continue until December 2031, allowing long-term follow-up and analysis.
CONDITIONS
Brief Title
Application of Biomarkers in Neurological Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with neurological diseases
- Subjects or legal agents agree to participate in the study and sign the informed consent.
You will not qualify if you...
- Participating in other clinical investigators
- Unwilling to be followed up or poor treatment compliance
- Other conditions considered unsuitable for inclusion by the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 months
Participants who undergo routine care are observed with collection of clinical data, laboratory data, imaging data, and biological samples at different time points in the acute and chronic phases.
Multiple visits depending on acute and chronic phase assessments
Trial Site Locations
Total: 1 location
1
First Hospital of Jilin University
Changchun, Jilin, China, 130000
Actively Recruiting
Research Team
Y
Yi YY Yang, Ph.D.
Z
Zhen-Ni GZ GUO, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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