Actively Recruiting
Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate
Led by University of Calgary · Updated on 2026-05-07
20
Participants Needed
1
Research Sites
329 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators will seek to determine the relationship between heart rate and middle cerebral artery (MCA) cerebral blood flow (CBF), as well as better understand the hemodynamic determinants of MCA CBF velocity. In order to manipulate heart rate, the investigators will recruit patients already scheduled for clinically indicated elective electrophysiological studies, where temporary pacing catheters placed in the right atrium can be used to artificially pace the heart at controlled rates. MCA CBF will be measured by transcranial Doppler ultrasound.
CONDITIONS
Official Title
Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female
- Age 18-70 years, inclusive
- Scheduled for clinically indicated elective electrophysiological studies where temporary pacing catheters are being placed in the right atrium
- Left ventricular ejection fraction 6550%
- Able and willing to provide informed consent
- Able to travel to the Cardiac Electrophysiology Laboratory at the Foothills Medical Centre, Calgary, Alberta, Canada
You will not qualify if you...
- Unable or unwilling to provide informed consent
- Other factors which in the investigator's opinion would prevent the participant from completing the protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Foothills Medical Center
Calgary, Alberta, Canada, T2N 4Z6
Actively Recruiting
Research Team
S
Satish R Raj, MD MSCI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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