Actively Recruiting

Age: 18Years +
All Genders
NCT05893407

Brain PERfusion Evaluation by Contrast-Enhanced UltraSound

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-06-19

60

Participants Needed

1

Research Sites

101 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of the study is to assess brain tissue perfusion by contrast-enhanced ultrasound perfusion imaging (PerCEUS) in acute brain injuries. More precisely, it aims : * to evaluate the heterogeneity of brain perfusion and thus diagnose brain tissue hypoperfusion with contrast-enhanced ultrasound. * to correlate contrast-enhanced ultrasound with perfusion measurements by usual multimodal monitoring.

CONDITIONS

Official Title

Brain PERfusion Evaluation by Contrast-Enhanced UltraSound

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Admission to intensive care unit for acute brain injury
  • Acute brain injury confirmed by CT and/or MRI
  • Requiring contrast ultrasound imaging
  • Informed consent given by patient or relative
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Insufficient temporal window for ultrasound
  • Contraindications to Sonovue contrast agent such as acute coronary syndromes, severe ischemic heart disease needing revascularization, pulmonary arterial hypertension above 90 mmHg, right-left shunt, ARDS, use of dobutamine, or known allergy to Sonovue
  • Patient under State Medical Assistance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Lariboisière Hospital

Paris, France, 75010

Actively Recruiting

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Research Team

R

Romain BARTHELEMY, MD

CONTACT

B

Benjamin Glenn CHOUSTERMAN, MD PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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