Actively Recruiting
Association of Urinary Tract Infection With Preeclampsia During Pregnancy
Led by Pakistan Air Force (PAF) Hospital Islamabad · Updated on 2025-05-08
160
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Urinary tract infections (UTIs) are a major clinical issue, especially in pregnant women, due to physiological changes that increase susceptibility. If untreated, UTIs can lead to severe complications like preterm labor and low birth weight. Preeclampsia, a hypertensive disorder affecting 0.2-9.2% of pregnancies, is another leading cause of maternal and fetal complications. The relationship between UTIs and preeclampsia remains controversial, with some studies suggesting an association while others show conflicting results. Research gaps highlight the need for region-specific studies, particularly in Pakistan, where both conditions contribute significantly to maternal and neonatal morbidity. This study aims to investigate the association between UTIs and preeclampsia in pregnant women in Pakistan. It will use a cohort design, enrolling 160 patients (80 with UTIs, 80 without) from the Obstetrics Department of PAF Hospital, Islamabad. Participants will be followed until delivery, with preeclampsia diagnosed based on blood pressure and proteinuria criteria. Data will be analyzed using SPSS to calculate relative risk (RR), with statistical significance set at RR \>1 and p ≤ 0.05. The findings could help improve prenatal care and reduce adverse outcomes in high-risk populations.
CONDITIONS
Official Title
Association of Urinary Tract Infection With Preeclampsia During Pregnancy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients attending outpatient department for routine antenatal checkup
- Diagnosed with urinary tract infection as defined by study criteria
- Gestational age greater than 20 weeks based on last menstrual period
- Age between 18 and 35 years
You will not qualify if you...
- History of diabetes mellitus
- History of chronic hypertension
- History of chronic liver or kidney diseases
- History of chronic pulmonary conditions
- History of urological surgery within the past 3 months
- History of renal transplants
- Currently on immunosuppressive therapy
- History of gestational diabetes mellitus
- History of hypertension
- History of chronic hepatic diseases
- History of ischemic heart disease
AI-Screening
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Trial Site Locations
Total: 1 location
1
PAF Hospital, Islamabad
Islamabad, Pakistan, 45100
Actively Recruiting
Research Team
W
Wajiha Fatima Resident, MBBS, FCPS (I)
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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