Actively Recruiting

Phase Not Applicable
Age: 21Years - 50Years
FEMALE
Healthy Volunteers
NCT06825936

Asian-Mediterranean Diet and Women's Health

Led by Global Centre for Asian Women's Health · Updated on 2025-03-12

300

Participants Needed

1

Research Sites

85 weeks

Total Duration

On this page

Sponsors

G

Global Centre for Asian Women's Health

Lead Sponsor

Y

Yong Loo Lin School of Medicine

Collaborating Sponsor

AI-Summary

What this Trial Is About

Given the escalating high burdens of overeight and obesity, and related commobidies in Asia, Asian women with overweight/obesity is an important group for targeted intervention in promoting health and wellbeing. A study focused on Asian women at reproductive or early post-menopausal age can inform effective strategies for promoting healthy diet and lifetyle and for optimizing health not only among these women but also for their children and partners. The Mediterranean diet has beneficial effects on cardiometabolic and reproductive health. So far, evidence on the Mediterranean diet and its health benefits mostly come from Western populations. Studies evaluating health effects of Mediterranean diet in Asian population are scant. This study aims to investigate the beneficial effects of a healthy, Mediterranean-inspired localized diet (i.e., Asian-Mediterranean diet) on women's health, such as cardiometabolic health with potential mechanisms through modulating gut and brain health.

CONDITIONS

Official Title

Asian-Mediterranean Diet and Women's Health

Who Can Participate

Age: 21Years - 50Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female aged 21-50 years
  • Chinese ethnicity
  • Singapore citizens, permanent residents, or long-term pass holders
  • Able to complete questionnaires in English
  • Body Mass Index (BMI) between 23.0 kg/m2 and less than 37.5 kg/m2
  • Not planning to conceive in the next 12 months from enrollment
  • Not planning to leave Singapore for more than 2 consecutive weeks in the next 6 months from enrollment
  • Not currently pregnant or breastfeeding
  • Not currently smoking
  • No history of major chronic diseases such as cancer, diabetes, cardiovascular diseases, or chronic kidney disease
  • No history of major infectious diseases like hepatitis B or HIV
  • No severe gastrointestinal disorders such as colitis, celiac disease, or chronic gastritis
  • No major mental health conditions
  • No known food allergies, especially to nuts and seafood
  • Not on special diets or dietary restrictions such as vegetarian, vegan, ketogenic, or Kosher
  • Not currently enrolled and will not enroll in other interventional studies affecting weight, cardiometabolic health, gut, or brain health in the next 6 months from enrollment
Not Eligible

You will not qualify if you...

  • Does not meet all inclusion criteria
  • For MRI procedure only: shoulder width 60 cm or more
  • Has medical implants or foreign bodies related to heart, brain, or eyes, including pacemakers, artificial heart valves, defibrillators, ventricular assist devices, brain stimulation devices, intrauterine devices, or breast biopsies
  • History of head injury or trauma with loss of consciousness
  • Metallic dental braces or dental implants
  • Claustrophobia
  • Consumes more than 30 units of alcohol per week (where 1 unit equals 25 mL of 40% spirit, 1 can of beer equals 2 units, 1 glass of wine equals 2 units)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Global Centre for Asian Women's Health

Singapore, Singapore, Singapore, 117549

Actively Recruiting

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Research Team

J

Jiaxi Yang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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